Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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U107242-20mg | 20mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $38.90 |
Pentacyclic triterpenoid; antitumourigenic.
Synonyms | 3beta-Hydroxyurs-12-en-28-oic acid | (+)-Ursolic acid | Prunol;Urson;Malol | 3beta-Hydroxy-12-ursen-28-ic acid | Micromerol | (3beta)-3-Hydroxyurs-12-en-28-oic acid | 3β-Hydroxy-12-ursen-28-oic Acid |
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Specifications & Purity | analytical standard, ≥98.5% |
Biochemical and Physiological Mechanisms | Pentacyclic triterpenoid. Suppresses NF-κB activation in vitro . Antitumourigenic, antiangiogenic, anti-inflammatory and proapoptotic effects. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | (1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid |
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INCHI | InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 |
InChi Key | WCGUUGGRBIKTOS-GPOJBZKASA-N |
Canonical SMILES | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O |
Isomeric SMILES | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O |
PubChem CID | 64945 |
Molecular Weight | 456.7 |
Beilstein | 2228563 |
Enter Lot Number to search for COA:
Specific Rotation[α] | 61° (C=1,Pyridine) |
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Melt Point(°C) | 283-285°C |
Merck Index | 9890 |
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1. Lu Huang, Yingjie Guo, Tianqi Jin, Ke Yan, Xianglin Liu, Shuyang He, Lin Li, Ye Gong, Junyi Ma, Hang Yu, Zhoumin Lu, Yupeng Liu, Wuzi Dong, Fangxia Yang. (2023) Extraction of triterpene acids from loquat leaves via a novel hydrophobic deep eutectic solvent screened by COSMO-SAC model. Journal of Cleaner Production, 427 (6): (139274). [PMID:23299939] |
2. Ying Wang, Xiaodan Wu, Guansong Shao, Tao Wang, Zihan Wang, Bingyang Qin, Jingru Zhao, Zhiguo Liu, Yujie Fu. (2023) A cellulose-based intelligent temperature-sensitive molecularly imprinted aerogel reactor for specific recognition and enrichment of ursolic acid. JOURNAL OF CHROMATOGRAPHY A, 1706 (464225). [PMID:37541056] |
3. Qiang Lyu, Wanying Zheng, Qiyuan Shan, Lichuang Huang, Yiwen Wang, Lu Wang, Haodan Kuang, Muhammad Azam, Gang Cao. (2023) Expanding annotation of chemical compounds in hawthorn fruits and their variations in thermal processing using integrated mass spectral similarity networking. FOOD RESEARCH INTERNATIONAL, 172 (113114). [PMID:37689886] |
4. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi. (2023) Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes. Chinese Medicine, 18 (1): (1-20). [PMID:37280712] |
5. Jing-Qing Le, Fang Yang, Xun-Huan Song, Ke-Ke Feng, Ling-Wu Tong, Meng-Die Yin, Wen-Zhong Zhang, Ying-Qi Lin, Hui Wu, Jing-Wei Shao. (2023) A hemoglobin-based oxygen-carrying biomimetic nanosystem for enhanced chemo-phototherapy and hypoxia alleviation of hepatocellular carcinoma. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 123 (330). [PMID:] |
6. Chunmei Lai, Bingchen Zhang, Dongmiao Li, Xiarong Tan, Bangyue Luo, Jiangwen Shen, Linyan Li, Jingwei Shao. (2023) Rational design of a minimum nanoplatform for maximizing therapeutic potency: Three birds with one stone. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 635 (441). [PMID:36599242] |
7. Da-Shuang Fang, Chun-Ru Cheng, Ming-Hua Qiu, Xing-Rong Peng. (2023) Diverse meroterpenoids with α-glucosidase inhibitory activity from Ganoderma cochlear. FITOTERAPIA, 165 (105420). [PMID:36586625] |
8. Meiling Sun, Zhenghui Luo, Qi Yang, Chunxu Huang, Yu Kuang, Mei Kang, Jie Liu. (2023) An extract from Cyclocarya paliurus leaves inhibits growth of methicillin-resistant Staphylococcus aureus by disrupting the formation of cell division Z-ring. INDUSTRIAL CROPS AND PRODUCTS, 193 (116184). [PMID:] |
9. Liang Liu, Jia Chen, Xuejian Chang, Juan Qin, Hanpeng Lai, Xianwen Zhang. (2023) Phytochemical profiles and bioactivities of Parnassia palustris L.. European Journal of Integrative Medicine, 57 (102207). [PMID:] |
10. Bo-Yang Li, Jia-Cheng Qin, Yu-Feng Shen, Fei Yang, Tao Wang, Fei Ling, Gao-Xue Wang. (2023) A therapeutic agent of ursolic acid demonstrates potential application in aquaculture. VIRUS RESEARCH, 323 (198965). [PMID:36272540] |
11. Yanwei Xue, Fei Wang, Chunhua Zhou. (2022) Optimization of Ultrasonic Extraction of Triterpenes from Loquat Peel and Pulp and Determination of Antioxidant Activity and Triterpenoid Components. Foods, 11 (17): (2563). [PMID:36076748] |
12. Qianqian Mao, Juan Min, Rui Zeng, Haiqin Liu, Hao Li, Cao Zhang, Aixian Zheng, Jiumao Lin, Xiaolong Liu, Ming Wu. (2022) Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.. Theranostics, 12 (14): (6088-6105). [PMID:36168633] |
13. Li Zhang, Huaizhong Xing, Wei Liu, Zihan Wang, Yumin Hao, Huiping Wang, Wenjuan Dong, Yang Liu, Shaomin Shuang, Chuan Dong, Xiaojuan Gong. (2021) 11-Mercaptoundecanoic Acid-Functionalized Carbon Dots As a Ratiometric Optical Probe for Doxorubicin Detection. ACS Applied Nano Materials, 4 (12): (13734–13746). [PMID:] |
14. Shuai Xue,Jianli Yin,Jiawei Shao,Yuanhuan Yu,Linfeng Yang,Yidan Wang,Mingqi Xie,Martin Fussenegger,Haifeng Ye. (2017-02-06) A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.. Molecular therapy : the journal of the American Society of Gene Therapy, 25 ((2)): (443-455). [PMID:28153094] |
1. Mirza FJ & Zahid S. (2022) Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's disease.. Front Pharmacol, 13 (1058358). [PMID:36618920] |
2. Lu Huang, Yingjie Guo, Tianqi Jin, Ke Yan, Xianglin Liu, Shuyang He, Lin Li, Ye Gong, Junyi Ma, Hang Yu, Zhoumin Lu, Yupeng Liu, Wuzi Dong, Fangxia Yang. (2023) Extraction of triterpene acids from loquat leaves via a novel hydrophobic deep eutectic solvent screened by COSMO-SAC model. Journal of Cleaner Production, 427 (6): (139274). [PMID:23299939] |
3. Ying Wang, Xiaodan Wu, Guansong Shao, Tao Wang, Zihan Wang, Bingyang Qin, Jingru Zhao, Zhiguo Liu, Yujie Fu. (2023) A cellulose-based intelligent temperature-sensitive molecularly imprinted aerogel reactor for specific recognition and enrichment of ursolic acid. JOURNAL OF CHROMATOGRAPHY A, 1706 (464225). [PMID:37541056] |
4. Qiang Lyu, Wanying Zheng, Qiyuan Shan, Lichuang Huang, Yiwen Wang, Lu Wang, Haodan Kuang, Muhammad Azam, Gang Cao. (2023) Expanding annotation of chemical compounds in hawthorn fruits and their variations in thermal processing using integrated mass spectral similarity networking. FOOD RESEARCH INTERNATIONAL, 172 (113114). [PMID:37689886] |
5. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi. (2023) Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes. Chinese Medicine, 18 (1): (1-20). [PMID:37280712] |
6. Jing-Qing Le, Fang Yang, Xun-Huan Song, Ke-Ke Feng, Ling-Wu Tong, Meng-Die Yin, Wen-Zhong Zhang, Ying-Qi Lin, Hui Wu, Jing-Wei Shao. (2023) A hemoglobin-based oxygen-carrying biomimetic nanosystem for enhanced chemo-phototherapy and hypoxia alleviation of hepatocellular carcinoma. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 123 (330). [PMID:] |
7. Chunmei Lai, Bingchen Zhang, Dongmiao Li, Xiarong Tan, Bangyue Luo, Jiangwen Shen, Linyan Li, Jingwei Shao. (2023) Rational design of a minimum nanoplatform for maximizing therapeutic potency: Three birds with one stone. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 635 (441). [PMID:36599242] |
8. Da-Shuang Fang, Chun-Ru Cheng, Ming-Hua Qiu, Xing-Rong Peng. (2023) Diverse meroterpenoids with α-glucosidase inhibitory activity from Ganoderma cochlear. FITOTERAPIA, 165 (105420). [PMID:36586625] |
9. Meiling Sun, Zhenghui Luo, Qi Yang, Chunxu Huang, Yu Kuang, Mei Kang, Jie Liu. (2023) An extract from Cyclocarya paliurus leaves inhibits growth of methicillin-resistant Staphylococcus aureus by disrupting the formation of cell division Z-ring. INDUSTRIAL CROPS AND PRODUCTS, 193 (116184). [PMID:] |
10. Liang Liu, Jia Chen, Xuejian Chang, Juan Qin, Hanpeng Lai, Xianwen Zhang. (2023) Phytochemical profiles and bioactivities of Parnassia palustris L.. European Journal of Integrative Medicine, 57 (102207). [PMID:] |
11. Bo-Yang Li, Jia-Cheng Qin, Yu-Feng Shen, Fei Yang, Tao Wang, Fei Ling, Gao-Xue Wang. (2023) A therapeutic agent of ursolic acid demonstrates potential application in aquaculture. VIRUS RESEARCH, 323 (198965). [PMID:36272540] |
12. Yanwei Xue, Fei Wang, Chunhua Zhou. (2022) Optimization of Ultrasonic Extraction of Triterpenes from Loquat Peel and Pulp and Determination of Antioxidant Activity and Triterpenoid Components. Foods, 11 (17): (2563). [PMID:36076748] |
13. Qianqian Mao, Juan Min, Rui Zeng, Haiqin Liu, Hao Li, Cao Zhang, Aixian Zheng, Jiumao Lin, Xiaolong Liu, Ming Wu. (2022) Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.. Theranostics, 12 (14): (6088-6105). [PMID:36168633] |
14. Li Zhang, Huaizhong Xing, Wei Liu, Zihan Wang, Yumin Hao, Huiping Wang, Wenjuan Dong, Yang Liu, Shaomin Shuang, Chuan Dong, Xiaojuan Gong. (2021) 11-Mercaptoundecanoic Acid-Functionalized Carbon Dots As a Ratiometric Optical Probe for Doxorubicin Detection. ACS Applied Nano Materials, 4 (12): (13734–13746). [PMID:] |
15. Shuai Xue,Jianli Yin,Jiawei Shao,Yuanhuan Yu,Linfeng Yang,Yidan Wang,Mingqi Xie,Martin Fussenegger,Haifeng Ye. (2017-02-06) A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.. Molecular therapy : the journal of the American Society of Gene Therapy, 25 ((2)): (443-455). [PMID:28153094] |