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Vadadustat - 97%, high purity , Hypoxia-inducible factor prolyl hydroxylase 1 inhibitor, CAS No.1000025-07-9, Hypoxia-inducible factor prolyl hydroxylase 1 inhibitor

Moligand™

≥97%

CAS#: 1000025-07-9
Formula: C₁₄H₁₁ClN₂O₄
Molecular Weight: 306.701
PubChem CID: 23634441

Item Number

V171541

Grouped product items
SKU	Size	Availability	Price
V171541-5mg	5mg	In stock	$129.90
V171541-10mg	10mg	In stock	$205.90
V171541-50mg	50mg	In stock	$532.90
V171541-100mg	100mg	In stock	$750.90
V171541-200mg	200mg	In stock	$1,351.90

View related series

egl-9 family hypoxia inducible factor 1 Inhibitor egl-9 family hypoxia inducible factor 2 Inhibitor HIF/HIF Prolyl-Hydroxylase Metabolic Enzyme/Protease

Basic Description

Synonyms	N-[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]glycine \| AG-617/02036022 \| CS-6373 \| 4,4'-Methylenebis[phenyl isocyanate] \| Vadadustat \| BCP19497 \| Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]- \| US8722895, 10: {[5-(3-Chlorophenyl)-
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Hypoxia-inducible factor prolyl hydroxylase 1 inhibitor

Associated Targets(Human)

EGLN1 Tclin Egl nine homolog 1 (4 Activities)

Discover Target: EGLN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EGLN3 Tclin Egl nine homolog 3 (2 Activities)

Discover Target: EGLN3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EGLN2 Tclin Egl nine homolog 2 (0 Activities)

Discover Target: EGLN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VEGFA Tclin Vascular endothelial growth factor A (159 Activities)

Discover Target: VEGFA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGLN1 Tclin Egl nine homolog 1 (1702 Activities)

Discover Target: EGLN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGLN3 Tclin Egl nine homolog 3 (250 Activities)

Discover Target: EGLN3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 Activities)

Discover Target: HIF1AN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Danio rerio (3092 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A085R Prolyl 4-hydroxylase (72 Activities)

Discover Target: A085R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
INCHI	InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)
InChi Key	JGRXMPYUTJLTKT-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O
Isomeric SMILES	C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O
PubChem CID	23634441
Molecular Weight	306.701

PubChem CID

ChEMBL Ligand

BindingDB Ligand

DrugBank Ligand

RCSB PDB Ligand

CAS Registry No.

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
K2210073	Certificate of Analysis	Jul 29, 2022	V171541
K2210074	Certificate of Analysis	Jul 29, 2022	V171541
K2210075	Certificate of Analysis	Jul 29, 2022	V171541
K2210076	Certificate of Analysis	Jul 29, 2022	V171541
K2210079	Certificate of Analysis	Jul 29, 2022	V171541

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P319:Get medical help if you feel unwell.

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Vadadustat - 97%, high purity , Hypoxia-inducible factor prolyl hydroxylase 1 inhibitor, CAS No.1000025-07-9, Hypoxia-inducible factor prolyl hydroxylase 1 inhibitor

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

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