Vallesiachotamine, a known monoterpene indole alkaloid, possesses anti-tumor activity.
In Vitro
Vallesiachotamine induces G0/G1 arrest and increased the proportion of sub-G1 hypodiploid cells (at 11 μM and 22 μM) and this effect is not dependent on time of incubation. Vallesiachotamine acts by promoting G0/G1 cell cycle arrest, apoptosis and necrosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only.