Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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V298968-10ml | 10ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $18.90 | |
V298968-25ml | 25ml | In stock | $35.90 | |
V298968-100ml | 100ml | In stock | $88.90 | |
V298968-500ml | 500ml | In stock | $265.90 |
Synonyms | Depakene | Depakin chrono | EC 202-777-3 | VALPROIC ACID | VALPROIC ACID [EP MONOGRAPH] | (n-C3H7)2CHCOOH | Nu-Valproic | DTXCID803733 | Avugane | CHEBI:39867 | Depakin | PHL-valproic acid | VALPROIC ACID (MART.) | Propylvaleric acid | Acidum valproicum | |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of histone deacetylase 1 |
ALogP | 2.8 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-propylpentanoic acid |
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INCHI | InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10) |
InChi Key | NIJJYAXOARWZEE-UHFFFAOYSA-N |
Canonical SMILES | CCCC(CCC)C(=O)O |
Isomeric SMILES | CCCC(CCC)C(=O)O |
PubChem CID | 3121 |
Molecular Weight | 144.21 |
DrugBank Ligand | DB00313 |
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PubChem CID | 3121 |
CAS Registry No. | 99-66-1 |
ChEMBL Ligand | CHEMBL109 |
Wikipedia | Valproic_acid |
RCSB PDB Ligand | 2PP |
PEP | valproic acid |
DrugCentral Ligand | 2803, 2803 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2421779 | Certificate of Analysis | Feb 29, 2024 | V298968 |
C2421794 | Certificate of Analysis | Feb 29, 2024 | V298968 |
A2417108 | Certificate of Analysis | Jun 30, 2022 | V298968 |
B2401049 | Certificate of Analysis | Jun 30, 2022 | V298968 |
G2328041 | Certificate of Analysis | Jun 30, 2022 | V298968 |
H2202426 | Certificate of Analysis | Jun 30, 2022 | V298968 |
H2202466 | Certificate of Analysis | Jun 30, 2022 | V298968 |
H2202467 | Certificate of Analysis | Jun 30, 2022 | V298968 |
L2304064 | Certificate of Analysis | Jun 30, 2022 | V298968 |
Solubility | Solubility in water: Practically Insoluble; Degree of Solubility in water: 2 g/l 20 °C; Soluble in Chloroform,Ether,Methanol |
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Refractive Index | 1.425 |
Flash Point(°F) | 231.8 °F |
Flash Point(°C) | 111°C |
Boil Point(°C) | 220 °C |
Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage H360:May damage fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
Merck Index | 9913 |
1. Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu. (2024) A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut–brain axis. Food & Function, 15 (1): (387-400). [PMID:38099485] |
2. Meili Guo, Gang Zhang, Ruoli Zhao, Huizhen Ma, Yuxing Yan, Shuyu Yang, Jian Meng, You Huang, Xiao-Dong Zhang, Hao Wang, Ruiping Zhang. (2023) Ligand Engineering of Gold Nanoclusters for NIR-II Imaging. ACS Applied Nano Materials, 6 (17): (15945–15958). [PMID:] |
3. Peixin Li, Yanfang Sun, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Yinjian Hua, Guohua Jiang. (2023) Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 249 (126013). [PMID:37517761] |
1. Chuanchuan Wang, Weixuan Chen, Yishan Jiang, Xiao Xiao, Qianhui Zou, Jiarui Liang, Yu Zhao, Qianxu Wang, Tian Yuan, Rui Guo, Xuebo Liu, Zhigang Liu. (2024) A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut–brain axis. Food & Function, 15 (1): (387-400). [PMID:38099485] |
2. Meili Guo, Gang Zhang, Ruoli Zhao, Huizhen Ma, Yuxing Yan, Shuyu Yang, Jian Meng, You Huang, Xiao-Dong Zhang, Hao Wang, Ruiping Zhang. (2023) Ligand Engineering of Gold Nanoclusters for NIR-II Imaging. ACS Applied Nano Materials, 6 (17): (15945–15958). [PMID:] |
3. Peixin Li, Yanfang Sun, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Yinjian Hua, Guohua Jiang. (2023) Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 249 (126013). [PMID:37517761] |