Skip to the beginning of the images gallery

Valsartan - ≥98% (HPLC), high purity , CAS No.137862-53-4, Antagonist of AT 1 receptor

Moligand™
≥98%(HPLC)

CAS#: 137862-53-4
Formula: C₂₄H₂₉N₅O₃
Molecular Weight: 435.52
EC Number: 604-045-2,695-249-0
MDL number: MFCD00865840
PubChem CID: 60846

Item Number

V129241

Grouped product items
SKU	Size	Availability	Price
V129241-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90
V129241-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$164.90
V129241-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$739.90
V129241-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,662.90

Highly selective, potent, competitive AT 1 receptor antagonist

View related series

AT1 receptor Antagonist

Basic Description

Synonyms	valsartan\|137862-53-4\|Diovan\|Tareg\|CGP 48933\|Provas\|Exforge\|CGP-48933\|Prexxartan\|Valzaar\|Valtan\|(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid\|137863-60-6\|N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Valsartan is a nonpeptide AT1 (angiotensin II AT1-receptor) antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.Highly selective, potent, competitive AT 1 receptor antagonist (K i = 2.38 nM). Shows antihypertensi
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of AT 1 receptor
Note	Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Valsartan is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 μM. Valsartan is an orally active specific angiotensin II receptor blocker used for the treatment of hypertension A nonpeptide angiotensin II AT1 receptor antagonist.

Names and Identifiers

IUPAC Name	(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
INCHI	InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
InChi Key	ACWBQPMHZXGDFX-QFIPXVFZSA-N
Canonical SMILES	CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
Isomeric SMILES	CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
WGK Germany	3
Alternate CAS	137862-53-4
PubChem CID	60846
NSC Number	758927
MeSH Entry Terms	48933, CGP;CGP 48933;Diovan;Kalpress;Miten;N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine;Nisis;Provas;Tareg;Vals;valsartan
Molecular Weight	435.52

DrugBank Ligand

Wikipedia

ChEBI

CAS Registry No.

PubChem CID

ChEMBL Ligand

PEP

Reactome Reaction

Reactome Drug

DrugCentral Ligand

RCSB PDB Ligand

GPCRdb Ligand

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot Number	Certificate Type	Date	Item
K2127016	Certificate of Analysis	Sep 20, 2023	V129241
K2127017	Certificate of Analysis	Sep 20, 2023	V129241
E1526061	Certificate of Analysis	Jan 16, 2023	V129241
B2318250	Certificate of Analysis	Jan 05, 2023	V129241
B2318251	Certificate of Analysis	Jan 05, 2023	V129241
B2318252	Certificate of Analysis	Jan 05, 2023	V129241
H2407057	Certificate of Analysis	Jan 05, 2023	V129241
G2216548	Certificate of Analysis	Jun 10, 2022	V129241
E2027052	Certificate of Analysis	Apr 25, 2022	V129241

Solubility

Soluble in Ethanol and Methanol

Sensitivity

Moisture sensitive

Specific Rotation[α]

-65°C

Melt Point(°C)

117°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Warning
Hazard Statements	H412:Harmful to aquatic life with long lasting effects H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice.
WGK Germany	3
Merck Index	9916

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Valsartan - ≥98% (HPLC), high purity , CAS No.137862-53-4, Antagonist of AT 1 receptor

Basic Description

Product Properties

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator