VDAC1/Porin Antibody - Primary antibody, specific to VDAC1/Porin, Rabbit IgG

Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human VDAC1/Porin Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab133998
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab133998-10μl
10μl
In stock
$66.90
Ab133998-50μl
50μl
In stock
$189.90
Ab133998-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab133998-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,809.90

pAb; Rabbit anti Human VDAC1/Porin Antibody; WB, IHC; Unconjugated

Basic Description

Product NameVDAC1/Porin Antibody - Primary antibody, specific to VDAC1/Porin, Rabbit IgG
SynonymsN2441 antibody; OMP2 antibody; POR1 antibody; hVDAC1 antibody; MGC111064 antibody; Mitochondrial Porin antibody; Outer mitochondrial membrane protein porin 1 antibody; Plasmalemmal porin antibody; Porin 31HL antibody; Porin 31HM antibody; VDAC antibody; V
Specifications & PurityExactAb™, Validated, 0.1 mg/mL
Host speciesRabbit
SpecificityVDAC1/Porin
ImmunogenA synthetic peptide derived from human VDAC1 (AA 3-16).
Positive ControlWB: Raji, HEK293, A431, HeLa, THP-1, Jurkat, Hep G2, NIH/3T3 and C6 cell lysates. IHC: Human liver tissue.
ConjugationUnconjugated
GradeExactAb™, Validated
Product Description

Rabbit anti Human VDAC1/Porin Antibody, Polyclonal antibody, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.1 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

VDAC1/Porin Antibody (Ab133998) - Western Blot
All lanes: VDAC1/Porin Antibody (Ab133998) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 31 kDa
Observed band size: 31 kDa
Exposure time: 16.3 s

VDAC1/Porin Antibody (Ab133998) - IHC
Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1/Porin Antibody (Ab133998). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets(Human)

VDAC1 Tbio Voltage-dependent anion-selective channel protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
VDAC1 Tbio Voltage-dependent anion-selective channel protein 1 (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202794Certificate of AnalysisFeb 23, 2024 Ab133998
ZJ24F0202793Certificate of AnalysisFeb 23, 2024 Ab133998

Related Documents

References

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