VEGFA, CAS No.rp175377, fms related receptor tyrosine kinase 1;Agonist of kinase insert domain receptor;kinase insert domain receptor

Features and benefits
    Item Number
    rp175377
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp175377-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp175377-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product NameVEGFA, CAS No.rp175377
    Synonymsvascular endothelial growth factor A;vascular permeability factor (VPF);VEGF-A
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionfms related receptor tyrosine kinase 1;Agonist of kinase insert domain receptor;kinase insert domain receptor

    Associated Targets(Human)

    FLT1 Tclin Vascular endothelial growth factor receptor 1 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Product Specifications

    CASrp175377

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    Certificate of Analysis(COA)

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    Genetic information

    Alternate Namesvascular endothelial growth factor A;vascular permeability factor (VPF);VEGF-A
    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

    Related Documents

    References

    1. Backer MV, Backer JM.  (2001)  Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteins..  Bioconjug Chem,  12  (6): (1066-73).  [PMID:11716701] [10.1021/op500134e]
    2. Anderson CR, Rychak JJ, Backer M, Backer J, Ley K, Klibanov AL.  (2010)  scVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis..  Invest Radiol,  45  (10): (579-85).  [PMID:20733505] [10.1021/op500134e]
    3. Zachary IC.  (2011)  How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns..  Biochem Soc Trans,  39  (6): (1583-91).  [PMID:22103491] [10.1021/op500134e]
    4. Vempati P, Popel AS, Mac Gabhann F.  (2014)  Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning..  Cytokine Growth Factor Rev,  25  (1): (1-19).  [PMID:24332926] [10.1021/op500134e]

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