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Vialinin A - 95%, high purity , CAS No.858134-23-3, Inhibitor of ubiquitin specific peptidase 5

Item Number
V287012
Grouped product items
SKUSizeAvailabilityPrice Qty
V287012-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$79.90
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Inhibitor of USP4 and USP5/IsoT

View related series
ubiquitin specific peptidase 5 Inhibitor

Basic Description

SynonymsAKOS024458452 | BDBM50437693 | [3,4-dihydroxy-2,5-bis(4-hydroxyphenyl)-6-(2-phenylacetyl)oxyphenyl] 2-phenylacetate | Terrestrin A | Vialinin A | GTPL8669 | NOJUKCRPSUMHQQ-UHFFFAOYSA-N | DTXSID00468621 | HY-103435 | 4,4'',5',6'-Tetrahydroxy[1,1':4',1''-te
Specifications & PurityMoligand™, ≥95%
Biochemical and Physiological MechanismsInhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50values are 1.5, 5.9 and 22.3μM, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decr
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of ubiquitin specific peptidase 5

Associated Targets(Human)

USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SENP1 Tchem Sentrin-specific protease 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CTSB Tchem Cathepsin B (3822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UCHL1 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L1 (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SENP1 Tchem Sentrin-specific protease 1 (681 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP8 Tchem Ubiquitin carboxyl-terminal hydrolase 8 (245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP4 Tchem Ubiquitin carboxyl-terminal hydrolase 4 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

RBL-2H3 (1162 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mast cell (119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [3,4-dihydroxy-2,5-bis(4-hydroxyphenyl)-6-(2-phenylacetyl)oxyphenyl] 2-phenylacetate
INCHI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2
InChi Key NOJUKCRPSUMHQQ-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)CC(=O)OC2=C(C(=C(C(=C2C3=CC=C(C=C3)O)O)O)C4=CC=C(C=C4)O)OC(=O)CC5=CC=CC=C5
Isomeric SMILES C1=CC=C(C=C1)CC(=O)OC2=C(C(=C(C(=C2C3=CC=C(C=C3)O)O)O)C4=CC=C(C=C4)O)OC(=O)CC5=CC=CC=C5
PubChem CID 11563133
Molecular Weight 562.57

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
H2308979Certificate of AnalysisJul 25, 2023 V287012
H2308984Certificate of AnalysisJul 25, 2023 V287012
G2229427Certificate of AnalysisJun 20, 2022 V287012
G2229428Certificate of AnalysisJun 20, 2022 V287012

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 11.25, Max Conc. mM: 20

Related Documents

 SDS

 Specification Sheet

References

1. Okada K, Ye YQ, Taniguchi K, Yoshida A, Akiyama T, Yoshioka Y, Onose J, Koshino H, Takahashi S, Yajima A et al..  (2013)  Vialinin A is a ubiquitin-specific peptidase inhibitor..  Bioorg Med Chem Lett,  23  (15): (4328-31).  [PMID:23791076] [10.1021/op500134e]

Solution Calculators

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