Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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V136673-10mg | 10mg | In stock | $61.90 | |
V136673-50mg | 50mg | In stock | $228.90 | |
V136673-100mg | 100mg | In stock | $410.90 | |
V136673-250mg | 250mg | In stock | $923.90 |
Irreversible inhibitor of GABA transaminase
Synonyms | vigabatrin | 4-aminohex-5-enoic acid | 60643-86-9 | Sabril | 68506-86-5 | 4-Amino-5-hexenoic acid | gamma-Vinyl GABA | Vigabatrine | 5-Hexenoic acid, 4-amino- | gamma-Vinyl-GABA | gamma Vinyl GABA | Vigabatrinum | MDL-71754 | 4-Aminohexenoic acid | gamma-Vinyl-gamma-Aminobutyric Aci |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Irreversible inhibitor of GABA transaminase (GABA-T). Increases GABA concentrations in the brain. Anticonvulsant and induces neuronal plasticity in mouse models. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | INHIBITOR |
Mechanism of action | Gamma-amino-N-butyrate transaminase inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Vigabatrin is a selective ABAT (GABA transaminase (T)) inhibitor. |
ALogP | -2.2 |
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IUPAC Name | 4-aminohex-5-enoic acid |
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INCHI | InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) |
InChi Key | PJDFLNIOAUIZSL-UHFFFAOYSA-N |
Canonical SMILES | C=CC(CCC(=O)O)N |
Isomeric SMILES | C=CC(CCC(=O)O)N |
WGK Germany | 1 |
PubChem CID | 5665 |
Molecular Weight | 129.16 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2215458 | Certificate of Analysis | May 10, 2024 | V136673 |
G2215455 | Certificate of Analysis | May 10, 2024 | V136673 |
G2215454 | Certificate of Analysis | Apr 15, 2024 | V136673 |
G2215459 | Certificate of Analysis | Apr 15, 2024 | V136673 |
E2225285 | Certificate of Analysis | Mar 13, 2024 | V136673 |
E2225286 | Certificate of Analysis | Mar 13, 2024 | V136673 |
E2225292 | Certificate of Analysis | Mar 13, 2024 | V136673 |
E2225295 | Certificate of Analysis | Mar 13, 2024 | V136673 |
K2020193 | Certificate of Analysis | Sep 20, 2022 | V136673 |
K2020190 | Certificate of Analysis | Sep 20, 2022 | V136673 |
Solubility | Soluble in water (19.60 - 20.40 mg/ml), ethanol, DMSO, DMF, and PBS, pH=7.2 (~10 mg/ml).. |
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Refractive Index | 1.48 |
Flash Point(°F) | 48.2 °F |
Flash Point(°C) | 9 °C |
Boil Point(°C) | 277.70° C at 760 mmHg |
Melt Point(°C) | 209° C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 1 |