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Vincristine sulfate - meets USP testing specifications, high purity , CAS No.2068-78-2

1 Citations

PharmPure™

USP

CAS#: 2068-78-2
Formula: C₄₆H₅₆N₄O₁₀·H₂SO₄
Molecular Weight: 923.04
Beilstein Registry Number: 3924631
EC Number: 218-190-0
PubChem CID: 249332

Item Number

V432299

Grouped product items
SKU	Size	Availability	Price
V432299-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$358.90
V432299-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,211.90
V432299-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,614.90

Basic Description

Synonyms	Vincristine sulfate \| 2068-78-2 \| Kyocristine \| Leurocristine sulfate \| Vincristine sulphate \| Vincrisul \| Novopharm \| 22-oxovincaleukoblastine sulfate \| NSC 67574 \| Oncovin \| Onkovin \| Vincrex \| Marqibo \| Vincristine, sulfate \| Leurocristine, sulfate \| VCR sulfate \| NSC67574 \| rel-Vincri
Specifications & Purity	PharmPure™, USP
Biochemical and Physiological Mechanisms	Vincristine sulfate possesses antitumor action targeting cell cycle. It prevents the action of tubulin by inhibiting microtubule polymerization. It also causes cell death and blocks metaphase in mitosis by preventing chromosome segregation. Vincristine su
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	PharmPure™, USP
Product Description	General Description Vincristine sulfate is an alkaloid present in Cantharanthus roseus . Application Vincristine sulfate has been used: as a positive control in potato disc anti-tumor bioassay as a standard cytotoxic agent to treat cells for manipulation of the microtubule network

Associated Targets(Human)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)

Discover Target: EHMT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GMNN Tbio Geminin (0 Activities)

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HIF1A Tchem Hypoxia-inducible factor 1-alpha (0 Activities)

Discover Target: HIF1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KAT2A Tchem Histone acetyltransferase KAT2A (0 Activities)

Discover Target: KAT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TUBA1A Tchem Tubulin alpha-1A chain (0 Activities)

Discover Target: TUBA1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (0 Activities)

Discover Target: SMAD3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RAB9A Tbio Ras-related protein Rab-9A (0 Activities)

Discover Target: RAB9A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LMNA Tbio Prelamin-A/C (0 Activities)

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase (0 Activities)

Discover Target: GAA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (0 Activities)

Discover Target: ABCC2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (0 Activities)

Discover Target: ABCC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCC4 Tchem Multidrug resistance-associated protein 4 (0 Activities)

Discover Target: ABCC4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR0B1 Tbio Nuclear receptor subfamily 0 group B member 1 (0 Activities)

Discover Target: NR0B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (0 Activities)

Discover Target: BAZ2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATXN2 Tbio Ataxin-2 (0 Activities)

Discover Target: ATXN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (0 Activities)

Discover Target: ACHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCB11 Tchem Bile salt export pump (0 Activities)

Discover Target: ABCB11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)

Discover Target: ATAD5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BCHE Tclin Cholinesterase (0 Activities)

Discover Target: BCHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)

Discover Target: IDH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)

Discover Target: NPC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A 172 (535 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHN (49357 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Breast carcinoma cell (217 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CAKI-1 (44928 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCRF-CEM (65223 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

COLO 205 (50209 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DLD-1 (17511 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DMS-273 (14108 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DU-145 (51482 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HL-60 (67320 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HT-29 (80576 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

K562 (73714 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KM12 (47707 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

M14 (47487 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MOLT-4 (49676 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Panel NCI-60 (60 carcinoma cell lines) (1088 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NFF (353 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NSCLC (640 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-3 (48710 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-4 (44535 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-5 (45555 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OVCAR-8 (47708 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PC-3 (62116 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RPMI-8226 (44974 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXF 393 (41971 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXF 631 (11415 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SF-295 (48000 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-MEL-2 (46422 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-MEL-28 (48833 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-MEL-5 (47095 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SK-OV-3 (52876 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SN12C (47755 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SNB-19 (46794 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SNB-78 (14240 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TK-10 (45540 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U-251 (51189 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UACC-257 (46019 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UACC-62 (47335 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UO-31 (46270 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

XF498 (12972 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

786-0 (47912 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI/ADR-RES (33767 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

T47D (39041 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Panel breast (Carcinoma cell lines) (123 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNS cell (47 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Klebsiella pneumoniae (43867 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Acinetobacter baumannii (41033 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Saccharomyces cerevisiae (19171 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cryptococcus neoformans (21258 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Gallus gallus (1187 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rhesus monkey (3147 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

B16 (5829 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHO (4503 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P388 (20296 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P388/ADR (1216 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P388/S (109 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P388/VCR (52 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

4T1 (1737 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TUBB2B Tubulin (2175 Activities)

Discover Target: TUBB2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid
INCHI	InChI=1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+;/m1./s1
InChi Key	AQTQHPDCURKLKT-JKDPCDLQSA-N
Canonical SMILES	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Isomeric SMILES	CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Alternate CAS	57-22-7(free base)
PubChem CID	249332
UN Number	1544
Packing Group	I
Molecular Weight	923.04
Beilstein	3924631

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)	300 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H341:Suspected of causing genetic defects H300:Fatal if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice.
Class	6.1
Merck Index	9986

Citations of This Product

1. Ajmal Muhammad, Wei Jia-Wen, Zhao Yan, Liu Yi-Hong, Wu Ping-Ping, Li Yao-Qun. (2022) Derivative Matrix-Isopotential Synchronous Spectrofluorimetry and Hantzsch Reaction: A Direct Route to Simultaneous Determination of Urinary δ-Aminolevulinic Acid and Porphobilinogen. Frontiers in Chemistry, 10 [PMID:35711951]

References

1. Jarvis MF, Scott VE, McGaraughty S, Chu KL, Xu J, Niforatos W, Milicic I, Joshi S, Zhang Q, Xia Z. (2014) A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats.. Biochem Pharmacol, 89 (4): (536-44). [PMID:24726441]
2. K E HAMPEL,H GERHARTZ. (1964-01-01) [RESULTS OF CHEMOTHERAPY OF HEMOBLASTOSES WITH VINBLASTINE AND VINCRISTINE SULFATE].. Krebsforschung und Krebsbekampfung, 30 (97-104). [PMID:14283724]
3. . (2004-08-06) Vincristine liposomal--INEX: lipid-encapsulated vincristine, onco TCS, transmembrane carrier system--vincristine, vincacine, vincristine sulfate liposomes for injection, VSLI.. Drugs in R&D, 5 ((2)): (119-123). [PMID:15293876]
4. Lisa Schulmeister. (2004-09-21) Preventing vincristine sulfate medication errors.. Oncology nursing forum, 31 ((5)): (E90-E98). [PMID:15378106]
5. Jeffrey A Silverman,Steven R Deitcher. (2012-12-06) Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine.. Cancer chemotherapy and pharmacology, 71 ((3)): (555-564). [PMID:23212117]
6. Sang Min Lee,Won Sik Lee,Ho Jin Shin,Je-Jung Lee,Sang Kyun Sohn,Joon Ho Moon,Hyeon Seok Eom,Jong Ho Won,Kyoo-Hyung Lee,Je-Hwan Lee,Dae-Young Kim,Sung-Soo Yoon,Inho Kim,Chul Won Jung,Seok Jin Kim,Hawk Kim,Jae Hoon Lee,Hun-Mo Ryoo,Gyeong-Won Lee,Sung-Hyun Kim,Yeung-Chul Mun,Min Kyoung Kim,Young Don Joo. (2013-04-06) Escalated daunorubicin dosing as an induction treatment for Philadelphia-negative adult acute lymphoblastic leukemia.. Annals of hematology, 92 ((8)): (1101-1110). [PMID:23558905]
7. David Cunningham,Eliza A Hawkes,Andrew Jack,Wendi Qian,Paul Smith,Paul Mouncey,Christopher Pocock,Kirit M Ardeshna,John A Radford,Andrew McMillan,John Davies,Deborah Turner,Anton Kruger,Peter Johnson,Joanna Gambell,David Linch. (2013-04-26) Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles.. Lancet (London, England), 381 ((9880)): (1817-1826). [PMID:23615461]
8. Matthew A Lunning,Alison J Moskowitz,Steven Horwitz. (2013-05-01) Strategies for relapsed peripheral T-cell lymphoma: the tail that wags the curve.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31 ((16)): (1922-1927). [PMID:23630204]
9. Arnold C Paulino,Ali Mazloom,Keita Terashima,Jack Su,Adekunle M Adesina,M Faith Okcu,Bin S Teh,Murali Chintagumpala. (2013-05-02) Intensity-modulated radiotherapy (IMRT) in pediatric low-grade glioma.. Cancer, 119 ((14)): (2654-2659). [PMID:23633429]
10. Kevin Johnson,David M Notrica,David Carpentieri,Dawn Jaroszewski,Michael M Henry. (2013-05-15) Successful treatment of recurrent pediatric inflammatory myofibroblastic tumor in a single patient with a novel chemotherapeutic regimen containing celecoxib.. Journal of pediatric hematology/oncology, 35 ((5)): (414-416). [PMID:23669730]
11. Minoru Mizutani,Yoshiki Nakamori,Haruna Sakaguchi,Yuki Kageyama,Eiko Oya,Kazuko Ino,Kei Suzuki,Takao Sekine. (2013-05-17) [Development of syndrome of inappropriate secretion of ADH and reversible posterior leukoencephalopathy during initial rituximab-CHOP therapy in a patient with diffuse large B-cell lymphoma].. [Rinsho ketsueki] The Japanese journal of clinical hematology, 54 ((3)): (269-272). [PMID:23676641]
12. Gautam Bhaumik,Koushik Chatterjee. (2013-06-08) Spindle cell sarcoma of the maxillary antrum.. Journal of the Indian Medical Association, 110 ((9)): (657-658). [PMID:23741844]
13. Yuksel Urun,Duygu Kankaya,Lokman Koral,Bulent Yalcin,Ayca Karabork,Koray Ceyhan,Melih Cem Boruban,Güngör Utkan,Ahmet Demirkazik. (2013-06-12) Intraabdominal follicular dendritic cell sarcoma: a report of three cases and review of the literature.. Tumori, 99 ((2)): (e65-e69). [PMID:23748832]
14. N V Sachivko,É A Zhavrid,E V Baranov,O A Kolenik. (2013-07-03) [Interleukin-2 (Ronkoleykin) in the first-line chemotherapy for B-cell non-Hodgkin lymphoma].. Voprosy onkologii, 59 ((2)): (52-58). [PMID:23814850]
15. Huynh Cao,Kenneth Yamamoto,Li-Xi Yang,Robert Weber. (2013-09-12) Brentuximab vedotin: first-line agent for advanced Hodgkin lymphoma.. Anticancer research, 33 ((9)): (3879-3885). [PMID:24023323]
16. James O Armitage. (2013-10-01) The aggressive peripheral T-cell lymphomas: 2013.. American journal of hematology, 88 ((10)): (910-918). [PMID:24078271]
17. Eri Yamamoto,Naoto Tomita,Seiji Sakata,Naoko Tsuyama,Kengo Takeuchi,Yuki Nakajima,Kazuho Miyashita,Takayoshi Tachibana,Hirotaka Takasaki,Masatsugu Tanaka,Chizuko Hashimoto,Hideyuki Koharazawa,Katsumichi Fujimaki,Jun Taguchi,Hiroshi Harano,Shigeki Motomura,Yoshiaki Ishigatsubo. (2013-10-12) MIB-1 labeling index as a prognostic factor for patients with follicular lymphoma treated with rituximab plus CHOP therapy.. Cancer science, 104 ((12)): (1670-1674). [PMID:24112697]
18. Yasuhiro Oki,Jason R Westin,Francisco Vega,Hubert Chuang,Nathan Fowler,Sattva Neelapu,Fredrick B Hagemeister,Peter McLaughlin,Larry W Kwak,Jorge E Romaguera,Michelle Fanale,Anas Younes,Maria Alma Rodriguez,Robert Z Orlowski,Michael Wang,Souzanne T Ouzounian,Felipe Samaniego,Luis Fayad. (2013-10-15) Prospective phase II study of rituximab with alternating cycles of hyper-CVAD and high-dose methotrexate with cytarabine for young patients with high-risk diffuse large B-cell lymphoma.. British journal of haematology, 163 ((5)): (611-620). [PMID:24117234]
19. Qin Huang. (2013-11-07) Cocirculating precursor B acute lymphoblastic leukemia and chronic lymphocytic leukemia.. Blood, 122 ((13)): (2148-2148). [PMID:24195124]
20. Akari Hashimoto,Akihito Fujimi,Yuji Kanisawa,Teppei Matsuno,Toshinori Okuda,Shinya Minami,Tadashi Doi,Kazuma Ishikawa,Naoki Uemura,Yuko Jyomen,Utano Tomaru. (2013-12-18) [Primary diffuse large B-cell lymphoma of the uterine cervix successfully treated with rituximabplus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy-a case report].. Gan to kagaku ryoho. Cancer & chemotherapy, 40 ((13)): (2589-2592). [PMID:24335377]
21. Hany R Guirguis,Matthew C Cheung,Eugenia Piliotis,David Spaner,Neil L Berinstein,Kevin Imrie,Liying Zhang,Rena Buckstein. (2014-01-15) Survival of patients with transformed lymphoma in the rituximab era.. Annals of hematology, 93 ((6)): (1007-1014). [PMID:24414374]
22. Alberto Soriano-Maldonado,María Hidalgo,Patricia Arteaga,Sonia de Pascual-Teresa,Esther Nova. (2014-02-18) Effects of regular consumption of vitamin C-rich or polyphenol-rich apple juice on cardiometabolic markers in healthy adults: a randomized crossover trial.. European journal of nutrition, 53 ((8)): (1645-1657). [PMID:24531755]
23. Virginie F Viprey,Walter M Gregory,Maria V Corrias,Andrei Tchirkov,Katrien Swerts,Ales Vicha,Sandro Dallorso,Penelope Brock,Roberto Luksch,Dominique Valteau-Couanet,Vassilios Papadakis,Genevieve Laureys,Andrew D Pearson,Ruth Ladenstein,Susan A Burchill. (2014-03-05) Neuroblastoma mRNAs predict outcome in children with stage 4 neuroblastoma: a European HR-NBL1/SIOPEN study.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32 ((10)): (1074-1083). [PMID:24590653]
24. Abraham Avigdor,Tsvi Sirotkin,Meirav Kedmi,Elena Ribakovsy,Miriam Berkowicz,Yaron Davidovitz,Abraham Kneller,Drorit Merkel,Yulia Volchek,Tima Davidson,Elinor Goshen,Sara Apter,Avichai Shimoni,Isaac Ben-Bassat,Arnon Nagler. (2014-03-07) The impact of R-VACOP-B and interim FDG-PET/CT on outcome in primary mediastinal large B cell lymphoma.. Annals of hematology, 93 ((8)): (1297-1304). [PMID:24595734]
25. Whitney W Stevens,Peter H S Sporn. (2014-04-02) Bilateral diaphragm weakness after chemotherapy for lymphoma.. American journal of respiratory and critical care medicine, 189 ((7)): (e12-e12). [PMID:24684366]
26. Eva Hoster,Wolfram Klapper,Olivier Hermine,Hanneke C Kluin-Nelemans,Jan Walewski,Achiel van Hoof,Marek Trneny,Christian H Geisler,Francesco Di Raimondo,Michal Szymczyk,Stephan Stilgenbauer,Catherine Thieblemont,Michael Hallek,Roswitha Forstpointner,Christiane Pott,Vincent Ribrag,Jeanette Doorduijn,Wolfgang Hiddemann,Martin H Dreyling,Michael Unterhalt. (2014-04-02) Confirmation of the mantle-cell lymphoma International Prognostic Index in randomized trials of the European Mantle-Cell Lymphoma Network.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32 ((13)): (1338-1346). [PMID:24687837]
27. Marcus Hentrich,Christian Hoffmann,Franz Mosthaf,Markus Müller,Jan Siehl,Christoph Wyen,Manfred Hensel. (2014-05-09) Therapy of HIV-associated lymphoma-recommendations of the oncology working group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), in cooperation with the German AIDS Society (DAIG).. Annals of hematology, 93 ((6)): (913-921). [PMID:24807241]
28. Adam J Olszewski,Eric S Winer,Jorge J Castillo. (2014-05-20) Improved survival with rituximab-based chemoimmunotherapy in older patients with extranodal diffuse large B-cell lymphoma.. Leukemia research, 38 ((8)): (866-873). [PMID:24837081]
29. Jessica L Heath,Shelly E Burgett,Ana M Gaca,Ronald Jaffe,Daniel S Wechsler. (2014-06-04) Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy.. Pediatric blood & cancer, 61 ((10)): (1874-1876). [PMID:24888336]
30. Armin Rashidi,Elaine M Maherus. (2014-06-07) After the treated mole.. Blood, 123 ((18)): (2757-2757). [PMID:24904937]
31. Mahua Mandal,Michelle J Hindin. (2014-07-25) Keeping it in the family: intergenerational transmission of violence in Cebu, Philippines.. Maternal and child health journal, 19 ((3)): (598-605). [PMID:25055760]
32. Graham W Slack,Christian Steidl,Laurie H Sehn,Randy D Gascoyne. (2014-08-20) CD30 expression in de novo diffuse large B-cell lymphoma: a population-based study from British Columbia.. British journal of haematology, 167 ((5)): (608-617). [PMID:25135752]
33. Grzegorz S Nowakowski,Betsy LaPlant,William R Macon,Craig B Reeder,James M Foran,Garth D Nelson,Carrie A Thompson,Candido E Rivera,David J Inwards,Ivana N Micallef,Patrick B Johnston,Luis F Porrata,Stephen M Ansell,Randy D Gascoyne,Thomas M Habermann,Thomas E Witzig. (2014-08-20) Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non-germinal center B-cell phenotype in newly diagnosed diffuse large B-Cell lymphoma: a phase II study.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33 ((3)): (251-257). [PMID:25135992]
34. Michelle A Fanale,Steven M Horwitz,Andres Forero-Torres,Nancy L Bartlett,Ranjana H Advani,Barbara Pro,Robert W Chen,Andrew Davies,Tim Illidge,Dirk Huebner,Dana A Kennedy,Andrei R Shustov. (2014-08-20) Brentuximab vedotin in the front-line treatment of patients with CD30+ peripheral T-cell lymphomas: results of a phase I study.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32 ((28)): (3137-3143). [PMID:25135998]
35. Abo Bakr Abdel Shakor,Mona Atia,Ismail Ahmed Ismail,Ali Alshehri,Hesham El-Refaey,Katarzyna Kwiatkowska,Andrzej Sobota. (2014-09-23) Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation.. Biochimica et biophysica acta, 1841 ((12)): (1672-1682). [PMID:25240837]
36. Jinlong Shi,Baolan Sun,Wei Shi,Hao Zuo,Daming Cui,Lanchun Ni,Jian Chen. (2014-10-07) Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36 ((2)): (655-662). [PMID:25283382]
37. Jacky Wong,Robert Welschinger,John Hewson,Kenneth F Bradstock,Linda J Bendall. (2014-11-02) Efficacy of dual PI-3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia.. Oncotarget, 5 ((21)): (10460-10472). [PMID:25361005]
38. Daniel O Persky,Thomas P Miller,Joseph M Unger,Catherine M Spier,Soham Puvvada,B Dino Stea,Oliver W Press,Louis S Constine,Kevin P Barton,Jonathan W Friedberg,Michael LeBlanc,Richard I Fisher. (2014-11-15) Ibritumomab consolidation after 3 cycles of CHOP plus radiotherapy in high-risk limited-stage aggressive B-cell lymphoma: SWOG S0313.. Blood, 125 ((2)): (236-241). [PMID:25395425]
39. Anand Babu,K G Prasanth,Bhaskar Balaji. (2014-11-29) Effect of curcumin in mice model of vincristine-induced neuropathy.. Pharmaceutical biology, 53 ((6)): (838-848). [PMID:25429779]
40. Victoria Cavaliere,Tomás Lombardo,Susana N Costantino,Laura Kornblihtt,Elida M Alvarez,Guillermo A Blanco. (2014-12-03) Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine.. European journal of cancer (Oxford, England : 1990), 50 ((18)): (3243-3261). [PMID:25446377]
41. He Huang,Xueying Li,Jun Zhu,Sheng Ye,Hongyu Zhang,Wei Wang,Xiangyuan Wu,Jiewen Peng,Bing Xu,Yingcheng. (2014-12-17) Entecavir vs lamivudine for prevention of hepatitis B virus reactivation among patients with untreated diffuse large B-cell lymphoma receiving R-CHOP chemotherapy: a randomized clinical trial.. JAMA, 312 ((23)): (2521-2530). [PMID:25514302]
42. Offiong F Ikpatt,Drury Reavill,Jason Chatfield,Susan Clubb,Joseph D Rosenblatt,Glenn Fonte,Yao-Shan Fan,Carolyn Cray. (2015-01-31) Diagnosis and treatment of diffuse large B-cell lymphoma in an orangutan (Pongo pygmaeus).. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 45 ((4)): (935-940). [PMID:25632687]
43. Howard L McLeod. (2015-02-25) Precision medicine to improve the risk and benefit of cancer care: genetic factors in vincristine-related neuropathy.. JAMA, 313 ((8)): (803-804). [PMID:25710656]
44. Hajime Asada,Hirotaka Tomiyasu,Yuko Goto-Koshino,Yasuhito Fujino,Koichi Ohno,Hajime Tsujimoto. (2015-02-27) Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines.. The Journal of veterinary medical science, 77 ((6)): (677-684). [PMID:25715778]
45. Ling-Yen Chiu,Ming-E Hu,Tsung-Ying Yang,I-Lun Hsin,Jiunn-Liang Ko,Kan-Jen Tsai,Gwo-Tarng Sheu. (2015-05-07) Immunomodulatory Protein from Ganoderma microsporum Induces Pro-Death Autophagy through Akt-mTOR-p70S6K Pathway Inhibition in Multidrug Resistant Lung Cancer Cells.. PloS one, 10 ((5)): (e0125774-e0125774). [PMID:25946033]
46. M Hugle,K Belz,S Fulda. (2015-05-30) Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.. Cell death and differentiation, 22 ((12)): (1946-1956). [PMID:26024389]
47. Eliane May de Lima,Carla Cristine Kanunfre,Lucas Ferrari de Andrade,Daniel Granato,Neiva Deliberali Rosso. (2015-09-04) Cytotoxic effect of inositol hexaphosphate and its Ni(II) complex on human acute leukemia Jurkat T cells.. Toxicology in vitro : an international journal published in association with BIBRA, 29 ((8)): (2081-2088). [PMID:26335902]
48. Scott R Pollack,David J Schenk. (2015-09-19) Site selective syntheses of [(3)H]omeprazole using hydrogen isotope exchange chemistry.. Journal of labelled compounds & radiopharmaceuticals, 58 ((11-12)): (433-441). [PMID:26380956]
49. Kieron Dunleavy,Stefania Pittaluga,Lauren S Maeda,Ranjana Advani,Clara C Chen,Julie Hessler,Seth M Steinberg,Cliona Grant,George Wright,Gaurav Varma,Louis M Staudt,Elaine S Jaffe,Wyndham H Wilson. (2013-04-12) Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma.. The New England journal of medicine, 368 ((15)): (1408-1416). [PMID:23574119]
50. Vivek Mangla,Sujoy Pal,Nihar Ranjan Dash,Prasenjit Das,Vineet Ahuja,Atul Sharma,Peush Sahni,Tushar Kanti Chattopadhyay. (2013-04-23) Rectal MALT lymphoma associated with ulcerative colitis.. Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 33 ((3)): (225-228). [PMID:23600057]
51. Konosuke Nakaji,Yukinori Nakae,Atsuyo Fujita,Mitsutaka Kumamoto,Yasushi Nakamura. (2013-11-06) [A case of melena and perforation during chemotherapy for peripheral T-cell lymphoma, not otherwise specified of the small intestine].. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 110 ((11)): (1950-1958). [PMID:24189824]
52. Robert S Nickel,Frank Keller,John Bergsagel,Todd Cooper,Marla Daves,Himalee Sabnis,Glen Lew. (2013-12-21) Mitoxantrone as a substitute for daunorubicin during induction in newly diagnosed lymphoblastic leukemia and lymphoma.. Pediatric blood & cancer, 61 ((5)): (810-814). [PMID:24357218]
53. Hee Sang Hwang,Chan-Sik Park,Dok Hyun Yoon,Cheolwon Suh,Jooryung Huh. (2014-04-08) High concordance of gene expression profiling-correlated immunohistochemistry algorithms in diffuse large B-cell lymphoma, not otherwise specified.. The American journal of surgical pathology, 38 ((8)): (1046-1057). [PMID:24705314]
54. Elizabeth A Old,Suchita Nadkarni,John Grist,Clive Gentry,Stuart Bevan,Ki-Wook Kim,Adrian J Mogg,Mauro Perretti,Marzia Malcangio. (2014-04-20) Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.. The Journal of clinical investigation, 124 ((5)): (2023-2036). [PMID:24743146]
55. Eric Borgstein,Steve Kamiza,Gordan Vujanic,Dalida Pidini,Simon Bailey,Tamiwe Tomoka,Kondwani Banda,Gertjan Kaspers,Elizabeth Molyneux,Trijn Israels. (2014-09-13) Wilms tumour in Malawi: surgical staging to stratify postoperative chemotherapy?. Pediatric blood & cancer, 61 ((12)): (2180-2184). [PMID:25213396]
56. Bruno Rodrigues Oliveira,Marcio Azevedo Figueiredo,Gilma Santos Trindade,Luis Fernando Marins. (2014-10-31) OCT4 mutations in human erythroleukemic cells: implications for multiple drug resistance (MDR) phenotype.. Molecular and cellular biochemistry, 400 ((1-2)): (41-50). [PMID:25355160]
57. Xiaofeng Zhai,Jianying Lu,Ying Wang,Fanfu Fang,Bai Li,Wei Gu. (2015-01-27) Reversal effect of bufalin on multidrug resistance in K562/VCR vincristine-resistant leukemia cell line.. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 34 ((6)): (678-683). [PMID:25618972]
58. Weiliang Chen,Donghai Wang,Xinwen Du,Ying He,Songyu Chen,Qianqian Shao,Chao Ma,Bin Huang,Anjing Chen,Peng Zhao,Xun Qu,Xingang Li. (2015-01-30) Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.. Medical oncology (Northwood, London, England), 32 ((3)): (43-43). [PMID:25631631]
59. Tadeusz Robak,Huiqiang Huang,Jie Jin,Jun Zhu,Ting Liu,Olga Samoilova,Halyna Pylypenko,Gregor Verhoef,Noppadol Siritanaratkul,Evgenii Osmanov,Julia Alexeeva,Juliana Pereira,Johannes Drach,Jiri Mayer,Xiaonan Hong,Rumiko Okamoto,Lixia Pei,Brendan Rooney,Helgi van de Velde,Franco Cavalli. (2015-03-05) Bortezomib-based therapy for newly diagnosed mantle-cell lymphoma.. The New England journal of medicine, 372 ((10)): (944-953). [PMID:25738670]
60. Ajmal Muhammad, Wei Jia-Wen, Zhao Yan, Liu Yi-Hong, Wu Ping-Ping, Li Yao-Qun. (2022) Derivative Matrix-Isopotential Synchronous Spectrofluorimetry and Hantzsch Reaction: A Direct Route to Simultaneous Determination of Urinary δ-Aminolevulinic Acid and Porphobilinogen. Frontiers in Chemistry, 10 [PMID:35711951]

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