Click Here for 5% Off Your First Aladdin Purchase!

Vinpocetine - 99%, high purity , CAS No.42971-09-5, Inhibitor of phosphodiesterase 1A;Inhibitor of phosphodiesterase 1C

  • Moligand™
  • ≥99%
Item Number
V107535
Grouped product items
SKUSizeAvailabilityPrice Qty
V107535-25mg
25mg
In stock
$20.90
V107535-100mg
100mg
In stock
$68.90
V107535-1g
1g
In stock
$621.90
V107535-5g
5g
In stock
$2,794.90
V107535-25g
25g
In stock
$12,575.90

Cell-permeable PDE1 inhibitor

Basic Description

Synonymsvinpocetine|42971-09-5|Cavinton|Ceractin|Apovincaminic acid ethyl ester|Bravinton|Ethyl apovincamin-22-oate|Ultra-Vinca|TCV-3B|RGH 4405|Ethyl (+)-apovincaminate|Vinporal|cis-Apovincaminic acid ethyl ester|RGH-4405|Ethyl apovincaminate|Ethyl (+)-cis-apovin
Specifications & Purity99%
Storage TempStore at -20°C
Shipped InDry ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of phosphodiesterase 1A;Inhibitor of phosphodiesterase 1C

Associated Targets

PDE1C Tclin Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE1A Tclin Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488189817
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189817
IUPAC Name ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
INCHI InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1
InChi Key DDNCQMVWWZOMLN-IRLDBZIGSA-N
Canonical SMILES CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC
Isomeric SMILES CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC
WGK Germany 3
RTECS JW4792000
PubChem CID 443955
Molecular Weight 350.45
Reaxy-Rn 900803

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot NumberCertificate TypeDateItem
G1213063Certificate of AnalysisApr 10, 2024 V107535
E23081180Certificate of AnalysisJan 13, 2023 V107535
E23081188Certificate of AnalysisJan 13, 2023 V107535
E23081213Certificate of AnalysisJan 13, 2023 V107535
E23081225Certificate of AnalysisJan 13, 2023 V107535
E23081231Certificate of AnalysisJan 13, 2023 V107535
E23081235Certificate of AnalysisJan 13, 2023 V107535
E23081259Certificate of AnalysisJan 13, 2023 V107535
E23081261Certificate of AnalysisJan 13, 2023 V107535
E23081264Certificate of AnalysisJan 13, 2023 V107535
A2304223Certificate of AnalysisJan 09, 2023 V107535
C2211488Certificate of AnalysisMay 31, 2022 V107535
C2202222Certificate of AnalysisMar 14, 2022 V107535

more

Chemical and Physical Properties

SolubilityDMSO : 6.25 mg/mL
SensitivityLight sensitive.
Specific Rotation[α]118° (C=2,Pyridine)
Melt Point(°C)151 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Hazard Statements

H302:Harmful if swallowed

WGK Germany 3
RTECS JW4792000
Reaxy-Rn 900803
Merck Index 9991

Related Documents

References

1. Lörincz C, Szász K, Kisfaludy L.  (1976)  The synthesis of ethyl apovincaminate..  Arzneimittelforschung,  26  (10a): (1907).  [PMID:1037211]
2. Szilágyi G, Nagy Z, Balkay L, Boros I, Emri M, Lehel S, Márián T, Molnár T, Szakáll S, Trón L et al..  (2005)  Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study..  J Neurol Sci,  229-230  (3): (275-84).  [PMID:15760651]
3. Sitges M, Galván E, Nekrassov V.  (2005)  Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes..  Neurochem Int,  46  (7): (533-40).  [PMID:15843047]
4. Hagiwara M, Endo T, Hidaka H.  (1984)  Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle..  Biochem Pharmacol,  33  (3): (453-7).  [PMID:6322804]
5. Truss MC, Uckert S, Stief CG, Forssmann WG, Jonas U.  (1996)  Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle. II. Effect of various PDE inhibitors on smooth muscle tone and cyclic nucleotide levels in vitro..  Urol Res,  24  (3): (129-34).  [PMID:8839479]

Solution Calculators