Vitamin C - 10mM in DMSO, high purity , CAS No.50-81-7(DMSO)

60 Citations
Item Number
V408646
Grouped product items
SKUSizeAvailabilityPrice Qty
V408646-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$158.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Information

Vitamin C (Ascorbic acid) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
In vitro

Ascorbate when combined with copper rapidly reduces the viscosity of DNA solutions and has exhibited some carcinostatic effects on transplanted sarcoma 180 tumours in mice. Exposure of HL-60 cells to increasing concentrations of H2O2 results in dose-dependent intracellular accumulation of peroxides, which is accompanied by a decrease in intracellular ascorbic acid and an increase in apoptosis. Ascorbic acid loading also provides strong protection from apoptosis associated with serum- and glucose-free culture of HL-60 cells. Vitamin C is found to protect GSH-depleted HL-60 cells in a dose-dependent manner. Vitamin C inhibits the formation of ROS in both normal and GSH-depleted cells. Ascorbate (1 mM) generates 161 mM H2O2 in Dulbecco\'s modified Eagle\'s medium and induces apoptosis in 50% of HL60 cells, whereas in RPMI 1640 only 83 mM H2O2 is produced and no apoptosis is detected.

In vivo

Treatment of rats with Vitamin C 10 min prior to the cisplatin inhibits cisplatin-mediated damage. The enhanced serum creatinine levels which are indicative of renal injury shows a significant reduction with the three doses of Vitamin C tested.
Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Associated Targets(Human)

ADRA2B Tclin Alpha-2B adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES OCC(O)C1OC(=O)C(=C1O)O
Molecular Weight 176.12

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Citations of This Product

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10. Zhang Ying, Li Chuan, Wei Qiushi, Yuan Qiang, He Wei, Zhang Ning, Dong Yiping, Jing Zhenhao, Zhang Leilei, Wang Haibin, Cao Xiangyang.  (2023)  MiRNA320a Inhibitor-Loaded PLGA-PLL-PEG Nanoparticles Contribute to Bone Regeneration in Trauma-Induced Osteonecrosis Model of the Femoral Head.  Tissue Engineering and Regenerative Medicine,    (1-13).  [PMID:37828392]
11. Weishen Zeng, Wenhua Yu, Jianhao Shen, Pu Chen, Zhizhen Shi, Guolie Xie, Yang Zhang, Hao Wang, Ning Guo.  (2023)  Tannic Acid-Inspired Antibacterial Hydrogel with Antioxidant and Anti-Inflammatory Properties for Staphylococcus aureus-Infected Wound Healing.  EUROPEAN POLYMER JOURNAL,    (112425).  [PMID:23232451]
12. Xiaoai Chen, Chunhe Gu, Kexue Zhu, Fei Xu, Zhen Feng, Yanjun Zhang.  (2024)  Insight into the effects of different ripeness levels on the quality and flavor chemistry of Noni fruit (Morinda citrifolia L.).  FOOD CHEMISTRY,  434  (137408).  [PMID:37716147]
13. Bowen Zheng, Peng Zhang, Qijun Lv, Tao Wu, Yadong Liu, Junjie Tang, Yanping Ma, Lili Cheng, Langtao Xu, Yizhen Wang, Yifan Xue, Jie Liu, Jie Ren.  (2024)  Development and preclinical evaluation of multifunctional hydrogel for precise thermal protection during thermal ablation.  Bioactive Materials,  31  (119).  [PMID:37637083]
14. Renshuang Sun, Zhongyuan Qu, Chenfeng Ji, Xiaolong Yang, Yiqiao Zhang, Xiang Zou.  (2023)  Optimum Reaction Conditions for the Synthesis of Selenized Ornithogalum caudatum Ait. (Liliaceae) Polysaccharides and Measurement of Their Antioxidant Activity In Vivo.  MOLECULES,  28  (15): (5929).  [PMID:37570899]
15. Li Yang, Fengxiang Zhang, Weiwei He, Boyuan Zhao, Ting Zhang, Shang Wang, Lifen Zhou, Junwei He.  (2024)  Extraction optimization and constituent analysis of total flavonoid from Hosta plantaginea (Lam.) Aschers flowers and its ameliorative effect on chronic prostatitis via inhibition of multiple inflammatory pathways in rats.  JOURNAL OF ETHNOPHARMACOLOGY,  318  (116922).  [PMID:37516390]
16. Yang Zhang, Shanshan Wang, Shitong You, Jun Wang, Jie Wang, Lixia Jia, Hongwei Zhang, Meng Zhang.  (2023)  Fabrication of transparent and hazy cellulosic light-management film for enhancing photon utilization in photocatalytic membrane process.  JOURNAL OF MEMBRANE SCIENCE,  685  (121923).  [PMID:]
17. Xiaoyi Long, Chaorui Deng, Gansheng Xiao, Fuliang Cheng, Ying Zhou, Lei Zhao, Longfei Cai, Jinyin Chen, Juan Du.  (2020)  Electrochemical Sensors with Antifouling Properties for Sensitive Detection of Isoproturon Based on Glassy Carbon Electrode Modified with Nafion Membrane.  International Journal of Electrochemical Science,  15  (4964).  [PMID:]
18. Muyi Li, Xiang Yang, Wenjun Liu, Huixian Wang, Hongmei Jiang, Xiaoying Liu.  (2021)  Ultrasensitive Determination of Dopamine and Uric Acid Based on Gold Nanoparticles@Carbon Dots/Electrochemical Reduced Graphene Oxide modified glassy carbon electrode.  International Journal of Electrochemical Science,  16  (21084).  [PMID:36271437]
19. Ke Xue, Yongfei Zhao, Saidong Sun, Yuanhang Li, Jiankang Liang, Zhengjian Qi.  (2023)  NIR-AIEgens nanospheres featuring high-fidelity dynamic lipid droplet targeting, expediting ferroptosis to annihilating tumor in hypoxia.  CHEMICAL ENGINEERING JOURNAL,  470  (144125).  [PMID:]
20. Cuiping Li, Mengfan Pang, Yaping Li, Lirong Han, Yajiao Fan, Xuelian Xin, Xian Zhang, Ning Zhang, Yan Qin.  (2023)  Protective effect of vitamin C against tetrachlorobenzoquinone-induced 5-hydroxymethylation-dependent apoptosis in HepG2 cells mainly via the mitochondrial apoptosis pathway.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  260  (115097).  [PMID:37271103]
21. Rong Ji, Yuming Dong, Hui Zhao, Chengsi Pan, Guangli Wang, Yongfa Zhu, Junshan Li.  (2023)  Z-scheme cobalt-iron oxide/perylene diimide supermolecule heterojunction for high-efficiency ciprofloxacin removal in a photocatalysis-self-Fenton system.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  648  (623).  [PMID:37321081]
22. Lei Jiang, Lin Yuan, Shan Gao, Yingying Xiang, Fei Song, Wensi Ma, Jing Wan, Xiuling Ji, Yujiao Tu.  (2023)  Facile hydrothermal synthesis of N-doped fluorescent carbon dots for selective detection of insecticide parathion.  Analytical Methods,  15  (19): (2376-2381).  [PMID:37132329]
23. Hu Lianying, Cheng Zhen, Wu Lunan, Luo Liangliang, Pan Ping, Li Shujin, Jia Qiyu, Yang Ning, Xu Bin.  (2023)  Histone methyltransferase SETDB1 promotes osteogenic differentiation in osteoporosis by activating OTX2-mediated BMP-Smad and Wnt/β-catenin pathways.  Human Cell,    (1-16).  [PMID:37074626]
24. Hui Shi, Ru Wang, Hu-Chen Cao, Hai-Yan Guo, Pei Pan, Cheng-Feng Xiong, Lin-Jun Zhang, Qiang Yang, Shuang Wei, Tao Liu.  (2023)  A Metal-Polyphenol-Based Oxygen Economizer and Fenton Reaction Amplifier for Self-Enhanced Synergistic Photothermal/Chemodynamic/Chemotherapy.  Advanced Healthcare Materials,    (2300054).  [PMID:36977362]
25. Yufen Liao, Xin Wang, Guangyun Ran, Shiyu Zhang, Chutian Wu, Rong Tan, Ying Liu, Yan He, Ting Liu, Zhongxiu Wu, Ying Peng, Weiwei Li, Jiang Zheng.  (2023)  DNA damage and up-regulation of PARP-1 induced by columbin in vitro and in vivo.  TOXICOLOGY LETTERS,  379  (20).  [PMID:36905973]
26. Ma Yinpeng, Zhang Piqi, Dai Xiaodong, Yao Xiuge, Zhou Shuyang, Ma Qingfang, Liu Jianing, Tian Shuang, Zhu Jianan, Zhang Jiechi, Kong Xianghui, Bao Yihong.  (2023)  Extraction, physicochemical properties, and antioxidant activity of natural melanin from Auricularia heimuer fermentation.  Frontiers in Nutrition,  10    [PMID:36875843]
27. Dongbao Cai, Xusheng Li, Qingjie Xu, Haiwei Li, Ruijing Liu, Jiali Chen, Xinwei Jiang, Jianxia Sun, Caiyong Lai, Weibin Bai.  (2023)  Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.  Food & Function,  14  (4): (2200-2211).  [PMID:36756975]
28. Yao Huang, Fengyu Tian, Leilei Sun, Chenhui Ji, Craig A. Grimes, Qingyun Cai.  (2023)  A glutathione-activated NIR-II fluorescent probe for precise localization of micrometastases.  SENSORS AND ACTUATORS B-CHEMICAL,  381  (133457).  [PMID:]
29. Lihuang Wu, Yuqi Wang, Xinyue Zhao, Hongli Mao, Zhongwei Gu.  (2023)  Investigating the Biodegradation Mechanism of Poly(trimethylene carbonate): Macrophage-Mediated Erosion by Secreting Lipase.  BIOMACROMOLECULES,  24  (2): (921–928).  [PMID:36644840]
30. Zhong-Xia Wang, Lei Hu, Xiao-Qiong Li, Yi-Lei Jia, Ting Wang, Wei Wang.  (2023)  Boron-enriched rice-like homologous carbon nanoclusters with a 51.5% photoluminescent quantum yield for highly sensitive determination of endogenous hydroxyl radicals in living cells.  Journal of Materials Chemistry B,  11  (7): (1523-1532).  [PMID:36688312]
31. Chu Youqun, Zhang Huixuan, Zhou Huihui, Xu Tengfei, Yan Hui, Huang Zhangkao, Zhao Fengming.  (2023)  L-tyrosine-assisted synthesis of nanosilver/titanium nitride with hollow microsphere structure for electrochemical detection of hydrogen peroxide.  JOURNAL OF SOLID STATE ELECTROCHEMISTRY,  27  (3): (753-761).  [PMID:]
32. Yujiao Tu, Ze Liu, Lei Jiang, Yingying Xiang, Fei Song, Lifen Meng, Xiuling Ji, Lin Yuan.  (2023)  Green ratiometric fluorescent dual-mode nanosensor for highly selective and sensitive detection of new coccine in food.  DYES AND PIGMENTS,  210  (111024).  [PMID:]
33. Qian Zhou, Shanshan Zhang, Xue Geng, Haiqiang Jiang, Yanpeng Dai, Ping Wang, Min Hua, Qi Gao, Shiyue Lang, Lijing Hou, Dianhua Shi, Meng Zhou.  (2022)  Antioxidant Effects of Roasted Licorice in a Zebrafish Model and Its Mechanisms.  MOLECULES,  27  (22): (7743).  [PMID:36431839]
34. Tianjian Dang, Guanghua Lu, Runren Jiang, Min Wang, Xiqiang Zheng.  (2023)  Bi-etched MIL-125 promotes visible-light-driven photocatalytic performance based on the surface plasmon resonance and spatial confinement effects.  SEPARATION AND PURIFICATION TECHNOLOGY,  306  (122597).  [PMID:]
35. Zhenyu Lu, Yufei Hu, Gongke Li, Ling Xia.  (2022)  Adamantane Three-Dimensional Porous Organic Framework as a Fluorescence Sensor for Rapid Determination of Tetracycline in Aquatic Products.  Chemosensors,  10  (11): (457).  [PMID:]
36. Lin Yuan, Lei Jiang, Ze Liu, Yingying Xiang, Fei Song, Yujiao Tu.  (2023)  Selective and sensitive simultaneous detection of tartrazine and Hg2+ based on N-doped yellow-green fluorescent carbon dots.  DYES AND PIGMENTS,  209  (110893).  [PMID:]
37. Guohong Wang, Jianxi Liu, Xiangcheng Liu, Minghang Li, Jiongjie Liu, Nan Chai, Fang Ye, Jimei Xue, Xiaomeng Fan, Hailong Xu, Xingmin Liu, Laifei Cheng.  (2023)  Oxidation-resistant vitamin C/MXene foam via surface hydrogen bonding for stable electromagnetic interference shielding in air ambient.  APPLIED SURFACE SCIENCE,  610  (155396).  [PMID:]
38. Xijuan Tu, Yunmin Tao, Jiaxu Chen, Chunping Du, Qian Jin, Yuchang He, Ji Yang, Shaokang Huang, Wenbin Chen.  (2022)  Dipicolinic Acid-Tb3+/Eu3+ Lanthanide Fluorescence Sensor Array for Rapid and Visual Discrimination of Botanical Origin of Honey.  Foods,  11  (21): (3388).  [PMID:36360001]
39. Junwen Liu, Jingwen Bai, Chuntian Shao, Shengnan Yao, Ran Xu, Suyang Duan, Libo Wang, Yaqin Xu, Yu Yang.  (2022)  Optimization of ultrasound-assisted aqueous two-phase extraction of polysaccharides from seabuckthorn fruits using response methodology, physicochemical characterization and bioactivities.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (6): (3168-3183).  [PMID:36268589]
40. Haiping Zhao, Ziyi Zhang, Yong Han, Weixia Yang, Wenzhi Tang, Tianli Yue, Zhonghong Li.  (2023)  Visual detection of vitamin C in fruits and vegetables using UiO-66 loaded Ce-MnO2 mimetic oxidase.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  285  (121900).  [PMID:36170775]
41. Juan Li, Gan Wang, Xiaoli Gou, Juan Xiang, Qiu-ting Huang, Guokun Liu.  (2022)  Revealing Trace Nanoplastics in Food Packages─An Electrochemical Approach Facilitated by Synergistic Attraction of Electrostatics and Hydrophobicity.  ANALYTICAL CHEMISTRY,  94  (37): (12657–12663).  [PMID:36070514]
42. Yaping Dai, Xuli Lu, Ruyi Li, Yupo Cao, Wei Zhou, Jihua Li, Baodong Zheng.  (2022)  Fabrication and Characterization of W/O/W Emulgels by Sipunculus nudus Salt-Soluble Proteins: Co-Encapsulation of Vitamin C and β-Carotene.  Foods,  11  (18): (2720).  [PMID:36140849]
43. Fada Wei, Qinghua Liu, Heqiang Liu, Guohong Wang, Minghang Li, Mingxing Li, Xingmin Liu.  (2022)  Advanced Ti3C2Tx MXene-modified cement nanocomposites toward high efficiency electromagnetic functional materials for green buildings.  International Journal of Applied Ceramic Technology,  20  (1): (251-260).  [PMID:]
44. Wei Chen, Binbin Yu, Xiaoqiang Zhang, Fanwei Zhang, Xingjie Zan, Tao Li.  (2023)  Precisely controlling the surface roughness of silica nanoparticles for enhanced functionalities and applications.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  629  (173).  [PMID:36081202]
45. Xuan Ding, Ziyi Wang, Bin Zheng, Shengchao Shi, Yibing Deng, Hanyang Yu, Peng Zheng.  (2022)  One-step asparaginyl endopeptidase (OaAEP1)-based protein immobilization for single-molecule force spectroscopy.  RSC Chemical Biology,  (10): (1276-1281).  [PMID:36320890]
46. Naiyi Yin, Zeliang Han, Wenbin Jia, Yaqi Fu, Jingnan Ma, Xiaotong Liu, Xiaolin Cai, Yan Li, Xiaochen Chen, Yanshan Cui.  (2022)  Effect of vitamin C supplement on lead bioaccessibility in contaminated soils using multiple in vitro gastrointestinal assays: Mechanisms and health risks.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  243  (113968).  [PMID:35981483]
47. Xiang Huang, Rui Tu, Hongbo Song, Kai Dong, Fang Geng, Lei Chen, Qun Huang, Yingmei Wu.  (2022)  Gelatin-EGCG-high methoxyl pectin ternary complex stabilized W1/O/W2 double emulsions loaded with vitamin C: Formation, structure, stability, in vitro gastrointestinal digestion.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  216  (891).  [PMID:35917852]
48. Yingying Xiang, Yujiao Tu, Lei Jiang, Lin Yuan, Ze Liu, Qiang Xie, Xuequan Xiong, Fei Song.  (2022)  Orange fluorescent dual-mode nanoprobe for selective and sensitive detection of amaranth based on S,N-Doped carbon dots.  DYES AND PIGMENTS,  205  (110533).  [PMID:]
49. Hongmei Xie, Juguo Dai, Lili Luo, Long Xia, Xiaohong Wang, Chunying Yang, Yiting Xu, Birong Zeng, Lizong Dai.  (2022)  Terpyridine-functionalized polyaniline/reduced graphene oxide composites for capturing Cr3+ ions and its application in supercapacitors.  Journal of Energy Storage,  52  (104965).  [PMID:]
50. Dan Li, Peipei Zhou, Yufei Hu, Gongke Li, Ling Xia.  (2022)  POSS-based fluorescence sensor for rapid analysis of β-carotene in health products.  LUMINESCENCE,  37  (8): (1290-1299).  [PMID:35614877]
51. Yi Feng, Hanxi Zhang, Xiaoxue Xie, Yu Chen, Geng Yang, Xiaodan Wei, Ningxi Li, Mengyue Li, Tingting Li, Xiang Qin, Shun Li, Fengming You, Chunhui Wu, Hong Yang, Yiyao Liu.  (2022)  Cascade-activatable NO release based on GSH-detonated “nanobomb” for multi-pathways cancer therapy.  Materials Today Bio,  14  (100288).  [PMID:35647513]
52. Wei Guo, Cui Liu, Nian Li, Min Xi, Yamin Che, Changlong Jiang, Shudong Zhang, Zhenyang Wang.  (2022)  A highly transparent and photothermal composite coating for effective anti-/de-icing of glass surfaces.  Nanoscale Advances,  (13): (2884-2892).  [PMID:36131998]
53. Shuwen Cheng, Danyao Tang, Yi Zhang, Libin Xu, Kunping Liu, Kejing Huang, Zhengzhi Yin.  (2022)  Specific and Sensitive Detection of Tartrazine on the Electrochemical Interface of a Molecularly Imprinted Polydopamine-Coated PtCo Nanoalloy on Graphene Oxide.  Biosensors-Basel,  12  (5): (326).  [PMID:35624626]
54. Shiyu Zhang, Ying Liu, Ting Liu, Jie Pan, Rong Tan, Zixia Hu, Bowen Gong, Yufen Liao, Peng Luo, Qibing Zeng, Weiwei Li, Jiang Zheng.  (2022)  DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo.  TOXICOLOGY AND APPLIED PHARMACOLOGY,  443  (116007).  [PMID:35367474]
55. Xiang Yingying, Song Fei, Jiang Lei, Liu Ze, Tu Yujiao.  (2022)  Novel Fluorescent Nano Carbon Quantum Dots Derived From Lactarius Hatsudake for High Selective Vitamin B12 Detection.  JOURNAL OF AOAC INTERNATIONAL,  105  (5): (1350-1359).  [PMID:35244160]
56. Wei Du, Hong-Min Fan, Yu-Xin Zhang, Xiao-Hua Jiang, Yun Li.  (2022)  Effect of Flavonoids in Hawthorn and Vitamin C Prevents Hypertension in Rats Induced by Heat Exposure.  MOLECULES,  27  (3): (866).  [PMID:35164138]
57. Yanna Pan, Shilin Yuan, Yilong Teng, Zeng Zhang, Yanming He, Ying Zhang, Haohui Liang, Xiao Wu, Jiaqi Li, Hongjie Yang, Ping Zhou.  (2022)  Antioxidation of a proteoglycan from Ganoderma lucidum protects pancreatic β-cells against oxidative stress-induced apoptosis in vitro and in vivo.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  200  (470).  [PMID:35063486]
58. H.L. Zhang, M.L. Wang, L.Z. Yi, P. Högger, R. Arroo, V.K. Bajpai, M.A. Prieto, X.J. Chen, J. Simal-Gandara, H. Cao.  (2022)  Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium.  FOOD CHEMISTRY,  378  (132033).  [PMID:35033717]
59. Meng Minjia, Zheng Jian, Cui Yanhua, Li Binrong, Yang Lili, Zhu Yu, Li Chunxiang.  (2022)  Freezing-assisted preparation of self-cleaning, high-flux photocatalytic nanocomposite membranes for enhanced degradation of antibiotic activity.  JOURNAL OF MATERIALS SCIENCE,  57  (1): (598-617).  [PMID:]
60. Henghui Zhang, Xiaoli Wang, Dongliang He, Dongliang Zou, Runzhu Zhao, Huifang Wang, Shuying Li, Yongping Xu, Buhailiqiemu Abudureheman.  (2022)  Optimization of Flavonoid Extraction from Xanthoceras sorbifolia Bunge Flowers, and the Antioxidant and Antibacterial Capacity of the Extract.  MOLECULES,  27  (1): (113).  [PMID:35011345]
61. Shixuan Su, Shanshan Li, Jing Hu, Ting Yu, Lingchen Tao, Fuliang Hu, Yunlei Xianyu.  (2022)  A colorimetric sensing strategy for detecting 10-hydroxy-2-decenoic acid in royal jelly based on Ag(I)-tetramethylbenzidine.  SENSORS AND ACTUATORS B-CHEMICAL,  354  (131241).  [PMID:]
62. Hui Guo, Jianwei Yu, Bingshuang Lei, Weiwei Ji, Huanhuan Liu, Bo Yin, Junqing Qian.  (2022)  T enzymatic esterification of naringin and the properties of naringin esterified derivatization.  INDUSTRIAL CROPS AND PRODUCTS,  176  (114372).  [PMID:]

Solution Calculators