Skip to the beginning of the images gallery

Vitamin D₃ solution - 100 μg/mL in ethanol, 97% (CP), high purity , Vitamin D receptor agonist, CAS No.67-97-0, Vitamin D receptor agonist

Moligand™
≥97%
100 μg/mL in ethanol

CAS#: 67-97-0
Formula: C₂₇H₄₄O
Molecular Weight: 384.64
Beilstein Registry Number: 2339331
EC Number: 200-673-2
PubChem CID: 5280795

Item Number

V433297

Grouped product items
SKU	Size	Availability	Price	Qty
V433297-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$422.90

View related series

Endogenous Metabolite Vitamin D Related/Nuclear Receptor

Basic Description

Synonyms	Vitamin D3\|cholecalciferol\|67-97-0\|Colecalciferol\|Calciol\|Ricketon\|Oleovitamin D3\|Deparal\|Arachitol\|Delsterol\|Trivitan\|Ebivit\|Vigantol\|Vigorsan\|vitamin d-3\|Colecalcipherol\|Colecalciferolum\|Cholecalciferolum\|D3-Vicotrat\|D3-Vigantol\|Vi-de-3-hydrosol\|NEO Doh
Specifications & Purity	Moligand™, ≥97%, 100 μg/mL in ethanol
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Vitamin D receptor agonist
Product Description	Gene Information human ... VDR(7421) General Description Vitamin D 3 is also known as cholecalciferol which promotes the absorption of calcium and phosphorus in the body that regulates bone growth. It is commonly found in humans and animals produced on our skin when exposed to sunlight. It facilitates bone growth and mineralization indirectly by enhancing plasma calcium and phosphorus levels. It is synthesized from 7-dehydrocholesterol, a derivative of cholesterol. Application Vitamin D 3 is used as an internal analytical standard for the quantitation of vitamin D 3 concentration in dietary supplements, fortified foods or within a complex biological matrix using a variety of testing applications. The active metabolite of vitamin D 3 is calcitriol (1,25-dihydroxyvitamin D 3 ) encapsulated into polymeric nanoparticles, which finds the application in vitamin D 3 -based chemotherapy formulation study and in vitro evaluation.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Discover Target: DRD2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD4 Tchem D(4) dopamine receptor 0 Activities

Discover Target: DRD4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 0 Activities

Discover Target: ERBB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Discover Target: GABRA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ELANE Tclin Neutrophil elastase 0 Activities

Discover Target: ELANE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor 0 Activities

Discover Target: EGFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

Discover Target: AVPR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0 Activities

Discover Target: HMGCR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

Discover Target: HRH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Discover Target: SLC6A3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Discover Target: SLC6A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

Discover Target: SIGMAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Discover Target: PTGS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Discover Target: CA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Discover Target: DRD3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities

Discover Target: KDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRNA7 Tchem Neuronal acetylcholine receptor subunit alpha-7 0 Activities

Discover Target: CHRNA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

Discover Target: CHRM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 0 Activities

Discover Target: CHRM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

Discover Target: ADRA2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

Discover Target: ADRA2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Discover Target: ADORA2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Discover Target: ACHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

Discover Target: ADRA1B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

Discover Target: ADRA1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Discover Target: AR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Discover Target: MAOA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AKR1B1 Tclin Aldose reductase 0 Activities

Discover Target: AKR1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Discover Target: ADORA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Discover Target: HTR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Discover Target: ADORA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

Discover Target: HTR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

Discover Target: HTR2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

F2 Tclin Prothrombin 0 Activities

Discover Target: F2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor 0 Activities

Discover Target: EDNRA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLRA1 Tclin Glycine receptor subunit alpha-1 1 Activities

Discover Target: GLRA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Discover Target: OPRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Discover Target: OPRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

Discover Target: NOS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TACR1 Tclin Substance-P receptor 0 Activities

Discover Target: TACR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain 0 Activities

Discover Target: NOS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
INCHI	InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChi Key	QYSXJUFSXHHAJI-YRZJJWOYSA-N
Canonical SMILES	CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C
Isomeric SMILES	C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
WGK Germany	2
RTECS	VS2900000
PubChem CID	5280795
UN Number	2811
Packing Group	I
Molecular Weight	384.64
Beilstein	2339331

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Sensitivity	Light sensitive
Specific Rotation[α]	108 ° (C=0.5, EtOH)
Melt Point(°C)	84-85°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled H372:Causes damage to organs through prolonged or repeated exposure
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	VS2900000
Class	6.1
Merck Index	10019

References

1. Fang-Rong Chang,Ken-ichiro Hayashi,Nam-Hai Chua,Shuichi Kamio,Zih-You Huang,Hiroshi Nozaki,Yang-Chang Wu. (2005-07-26) The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists.. Journal of natural products, 68 ((7)): (971-973). [PMID:16038533]
2. Upasana Banerjee,Manuka Ghosh,M Kyle Hadden. (2012-01-10) Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors.. Bioorganic & medicinal chemistry letters, 22 ((3)): (1330-1334). [PMID:22226657]
3. Umon Agata,Jong-Hoon Park,Satoshi Hattori,Yuki Iimura,Ikuko Ezawa,Takayuki Akimoto,Naomi Omi. (2013-03-29) The effect of different amounts of calcium intake on bone metabolism and arterial calcification in ovariectomized rats.. Journal of nutritional science and vitaminology, 59 ((1)): (29-36). [PMID:23535537]
4. A G Fuchs,C I Echeverría,F G Pérez Rojo,E A Prieto González,E J A Roldán. (2013-06-08) Proline modulates the effect of bisphosphonate on calcium levels and adenosine triphosphate production in cell lines derived from bovine Echinococcus granulosus protoscoleces.. Journal of helminthology, 88 ((4)): (459-467). [PMID:23742745]
5. Sheri L Pollock,Elizabeth A Rush,Robert L Redner. (2013-08-10) NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation.. Leukemia & lymphoma, 55 ((6)): (1383-1387). [PMID:23927396]
6. Xin Xu,Russell A Prough,David J Samuelson. (2013-09-07) Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway.. Molecular carcinogenesis, 54 ((2)): (134-147). [PMID:24008983]
7. Yuko Murakami,Masayoshi Fukasawa,Yukihiro Kaneko,Tetsuro Suzuki,Takaji Wakita,Hidesuke Fukazawa. (2013-11-02) Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling.. Microbes and infection, 16 ((2)): (114-122). [PMID:24177211]
8. Minyong Kang,Yong-Mahn Han. (2014-04-15) Differentiation of human pluripotent stem cells into nephron progenitor cells in a serum and feeder free system.. PloS one, 9 ((4)): (e94888-e94888). [PMID:24728509]
9. Anders Burild,Henrik L Frandsen,Jette Jakobsen. (2014-04-23) Simultaneous quantification of vitamin D₃, 25-hydroxyvitamin D₃ and 24,25-dihydroxyvitamin D₃ in human serum by LC-MS/MS.. Scandinavian journal of clinical and laboratory investigation, 74 ((5)): (418-423). [PMID:24749986]
10. Omar Z Ameer,Ibrahim M Salman,Alberto P Avolio,Jacqueline K Phillips,Mark Butlin. (2014-05-20) Opposing changes in thoracic and abdominal aortic biomechanical properties in rodent models of vascular calcification and hypertension.. American journal of physiology. Heart and circulatory physiology, 307 ((2)): (H143-H151). [PMID:24838503]
11. Miles D Witham,Rosemary J G Price,Allan D Struthers,Peter T Donnan,Martina Messow,Alex McConnachie,Ian Ford,Marion E T McMurdo. (2014-06-01) Effect of vitamin D supplementation on orthostatic hypotension: data from the vitamin D in isolated systolic hypertension randomized controlled trial.. Journal of hypertension, 32 ((8)): (1693-1699). [PMID:24879494]
12. Xiaocang Cao,Zhi-Bo Han,Hui Zhao,Qiang Liu. (2014-06-11) Transplantation of mesenchymal stem cells recruits trophic macrophages to induce pancreatic beta cell regeneration in diabetic mice.. The international journal of biochemistry & cell biology, 53 (372-379). [PMID:24915493]
13. Sunil K Halder,Chakradhari Sharan,Omar Al-Hendy,Ayman Al-Hendy. (2014-06-14) Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids.. Reproductive sciences (Thousand Oaks, Calif.), 21 ((9)): (1108-1119). [PMID:24925855]
14. Nicholas A McKeag,Michelle C McKinley,Mark T Harbinson,Rebecca L Noad,Lynn H Dixon,Ann McGinty,Charlotte E Neville,Jayne V Woodside,Pascal P McKeown. (2014-06-24) The effect of multiple micronutrient supplementation on left ventricular ejection fraction in patients with chronic stable heart failure: a randomized, placebo-controlled trial.. JACC. Heart failure, 2 ((3)): (308-317). [PMID:24952700]
15. Fuyuko Koibuchi,Natsumi Ritoh,Ryohei Aoyagi,Megumi Funakoshi-Tago,Hiroomi Tamura. (2014-07-06) Dexamethasone suppresses neurosteroid biosynthesis via downregulation of steroidogenic enzyme gene expression in human glioma GI-1 cells.. Biological & pharmaceutical bulletin, 37 ((7)): (1241-1247). [PMID:24989015]
16. Ming Kong,Longdong Zhu,Li Bai,Xiaohui Zhang,Yu Chen,Shuang Liu,Sujun Zheng,Stephen J Pandol,Yuan-Ping Han,Zhongping Duan. (2014-09-13) Vitamin D deficiency promotes nonalcoholic steatohepatitis through impaired enterohepatic circulation in animal model.. American journal of physiology. Gastrointestinal and liver physiology, 307 ((9)): (G883-G893). [PMID:25214402]
17. Ghaith Bakdash,Toni M M van Capel,Lauren M K Mason,Martien L Kapsenberg,Esther C de Jong. (2014-09-23) Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells.. Vaccine, 32 ((47)): (6294-6302). [PMID:25236584]
18. Kanako Moriyama,Akiko Kukita,Yin-Ji Li,Norihisa Uehara,Jing-Qi Zhang,Ichiro Takahashi,Toshio Kukita. (2014-09-30) Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction.. Laboratory investigation; a journal of technical methods and pathology, 94 ((11)): (1200-1211). [PMID:25264706]
19. Xiaoliang Zhang,Zhixia Song,Yinfeng Guo,Min Zhou. (2014-10-09) The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats.. Molecular and cellular biochemistry, 399 ((1-2)): (155-165). [PMID:25292315]
20. D Hamam,D Ali,R Vishnubalaji,R Hamam,M Al-Nbaheen,L Chen,M Kassem,A Aldahmash,N M Alajez. (2014-10-31) microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells.. Cell death & disease, 5 (e1499-e1499). [PMID:25356868]
21. Mei Ding,Daoyuan Si,Wenqi Zhang,Zhaohui Feng,Min He,Ping Yang. (2014-11-06) Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.. Experimental and therapeutic medicine, 8 ((6)): (1737-1744). [PMID:25371725]
22. Z H Ren,W Yuan,H D Deng,J L Deng,Q X Dan,H T Jin,C L Tian,X Peng,Z Liang,S Gao,S H Xu,G Li,Y Hu. (2014-11-19) Effects of antibacterial peptide on cellular immunity in weaned piglets.. Journal of animal science, 93 ((1)): (127-134). [PMID:25403191]
23. Jing Zhang,Jin-Rui Chang,Xiao-Hui Duan,Yan-Rong Yu,Bao-Hong Zhang. (2014-11-25) Thyroid hormone attenuates vascular calcification induced by vitamin D3 plus nicotine in rats.. Calcified tissue international, 96 ((1)): (80-87). [PMID:25416842]
24. P De Groote,H T Tran,M Fransen,G Tanghe,C Urwyler,B De Craene,K Leurs,B Gilbert,G Van Imschoot,R De Rycke,C J Guérin,P Holland,G Berx,P Vandenabeele,S Lippens,K Vleminckx,W Declercq. (2014-11-29) A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.. Cell death and differentiation, 22 ((6)): (1012-1024). [PMID:25430793]
25. M D Witham,F Adams,S McSwiggan,G Kennedy,G Kabir,J J F Belch,F Khan. (2014-12-03) Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.. Nutrition, metabolism, and cardiovascular diseases : NMCD, 25 ((3)): (287-294). [PMID:25455721]
26. Michael Haas,Christoph Kern,Stephan Kruger,Marlies Michl,Dominik P Modest,Clemens Giessen,Christoph Schulz,Jobst C von Einem,Steffen Ormanns,Rüdiger P Laubender,Stefan Holdenrieder,Volker Heinemann,Stefan Boeck. (2014-12-05) Assessing novel prognostic serum biomarkers in advanced pancreatic cancer: the role of CYFRA 21-1, serum amyloid A, haptoglobin, and 25-OH vitamin D3.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36 ((4)): (2631-2640). [PMID:25472579]
27. J L Adolphe,M D Drew,T I Silver,J Fouhse,H Childs,L P Weber. (2014-12-06) Effect of an extruded pea or rice diet on postprandial insulin and cardiovascular responses in dogs.. Journal of animal physiology and animal nutrition, 99 ((4)): (767-776). [PMID:25475789]
28. F Savino,S Ceratto,E Poggi,M E Cartosio,L Cordero di Montezemolo,A Giannattasio. (2014-12-10) Preventive effects of oral probiotic on infantile colic: a prospective, randomised, blinded, controlled trial using Lactobacillus reuteri DSM 17938.. Beneficial microbes, 6 ((3)): (245-251). [PMID:25488262]
29. Ahmed Alsaqr,Mohammed Rasoully,Florin Marcel Musteata. (2015-01-23) Investigating transdermal delivery of vitamin D3.. AAPS PharmSciTech, 16 ((4)): (963-972). [PMID:25609377]
30. Joan Hui Juan Lim,Sharada Ravikumar,Yan-Ming Wang,Thomas Paulraj Thamboo,Lizhen Ong,Jinmiao Chen,Jessamine Geraldine Goh,Sen Hee Tay,Lufei Chengchen,Mar Soe Win,Winnie Leong,Titus Lau,Roger Foo,Haris Mirza,Kevin Shyong Wei Tan,Sunil Sethi,Ai Leng Khoo,Wee Joo Chng,Motomi Osato,Mihai G Netea,Yue Wang,Louis Yi Ann Chai. (2015-01-24) Bimodal Influence of Vitamin D in Host Response to Systemic Candida Infection-Vitamin D Dose Matters.. The Journal of infectious diseases, 212 ((4)): (635-644). [PMID:25612733]
31. Melissa Jensen,Maisam Abu-El-Haija,Warren Bishop,Riad M Rahhal. (2015-02-05) Difficulty Achieving Vitamin D Sufficiency With High-Dose Oral Repletion Therapy in Infants With Cholestasis.. Journal of pediatric gastroenterology and nutrition, 61 ((2)): (187-189). [PMID:25651487]
32. Jianfeng Zhang,Yicheng Wu,Anqing Chen,Qiang Zhao. (2015-03-15) Mesenchymal stem cells promote cardiac muscle repair via enhanced neovascularization.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 35 ((3)): (1219-1229). [PMID:25766532]
33. Sara Neal,Jeannie Sykes,Michael Rigby,Bryan Hess. (2015-03-24) A review and clinical summary of vitamin D in regard to bone health and athletic performance.. The Physician and sportsmedicine, 43 ((2)): (161-168). [PMID:25797288]
34. Stefan Pilz,Martin Gaksch,Katharina Kienreich,Martin Grübler,Nicolas Verheyen,Astrid Fahrleitner-Pammer,Gerlies Treiber,Christiane Drechsler,Bríain Ó Hartaigh,Barbara Obermayer-Pietsch,Verena Schwetz,Felix Aberer,Julia Mader,Hubert Scharnagl,Andreas Meinitzer,Elisabeth Lerchbaum,Jacqueline M Dekker,Armin Zittermann,Winfried März,Andreas Tomaschitz. (2015-03-25) Effects of vitamin D on blood pressure and cardiovascular risk factors: a randomized controlled trial.. Hypertension (Dallas, Tex. : 1979), 65 ((6)): (1195-1201). [PMID:25801871]
35. Isa Gabriela de Medeiros Cavalcante,Alexandre Sérgio Silva,Maria José Carvalho Costa,Darlene Camati Persuhn,Chahira Taha Mahd Ibrahim Issa,ChariraTahaMad Ibraim Issa,Tiago Lima de Luna Freire,Maria da Conceição Rodrigues Gonçalves. (2015-04-02) Effect of vitamin D3 supplementation and influence of BsmI polymorphism of the VDR gene of the inflammatory profile and oxidative stress in elderly women with vitamin D insufficiency: Vitamin D3 megadose reduces inflammatory markers.. Experimental gerontology, 66 (10-16). [PMID:25827670]
36. Jamal S Lewis,Natalia V Dolgova,Ying Zhang,Chang Qing Xia,Clive H Wasserfall,Mark A Atkinson,Michael J Clare-Salzler,Benjamin G Keselowsky. (2015-04-07) A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice.. Clinical immunology (Orlando, Fla.), 160 ((1)): (90-102). [PMID:25842187]
37. Mu-En Lin,Theodore Chen,Elizabeth M Leaf,Mei Y Speer,Cecilia M Giachelli. (2015-05-20) Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice.. The American journal of pathology, 185 ((7)): (1958-1969). [PMID:25987250]
38. Dae-Jung Kang,Jong-Hyuk Im,Jae-Hoon Kang,Kyoung Heon Kim. (2015-05-23) Bioconversion of vitamin D3 to calcifediol by using resting cells of Pseudonocardia sp.. Biotechnology letters, 37 ((9)): (1895-1904). [PMID:25994584]
39. Li-Shu Guo,Hong-Xia Li,Chun-Yang Li,Sheng-Yan Zhang,Jia Chen,Qi-Long Wang,Jing-Miao Gao,Jia-Qi Liang,Ming-Tang Gao,Yong-Jie Wu. (2015-05-23) Synergistic antitumor activity of vitamin D3 combined with metformin in human breast carcinoma MDA-MB-231 cells involves m-TOR related signaling pathways.. Die Pharmazie, 70 ((2)): (117-122). [PMID:25997252]
40. Lan Ma,Reona Aijima,Yoshihiro Hoshino,Haruyoshi Yamaza,Erika Tomoda,Yosuke Tanaka,Soichiro Sonoda,Guangtai Song,Wei Zhao,Kazuaki Nonaka,Songtao Shi,Takayoshi Yamaza. (2015-05-28) Transplantation of mesenchymal stem cells ameliorates secondary osteoporosis through interleukin-17-impaired functions of recipient bone marrow mesenchymal stem cells in MRL/lpr mice.. Stem cell research & therapy, 6 (104-104). [PMID:26012584]
41. K L Little,B M Bohrer,T Maison,Y Liu,H H Stein,D D Boler. (2015-05-29) Effects of feeding canola meal from high-protein or conventional varieties of canola seeds on growth performance, carcass characteristics, and cutability of pigs.. Journal of animal science, 93 ((3)): (1284-1297). [PMID:26020905]
42. Jack C Cappozzo,Tatiana Koutchma,Gail Barnes. (2015-06-01) Chemical characterization of milk after treatment with thermal (HTST and UHT) and nonthermal (turbulent flow ultraviolet) processing technologies.. Journal of dairy science, 98 ((8)): (5068-5079). [PMID:26026762]
43. Sonia Tabasum Ahmed,Md Manirul Islam,A B M Rubayet Bostami,Hong-Seok Mun,Ye-Jin Kim,Chul-Ju Yang. (2015-06-05) Meat composition, fatty acid profile and oxidative stability of meat from broilers supplemented with pomegranate (Punica granatum L.) by-products.. Food chemistry, 188 (481-488). [PMID:26041221]
44. W P Weiss,E Azem,W Steinberg,T A Reinhardt. (2015-06-09) Effect of feeding 25-hydroxyvitamin D3 with a negative cation-anion difference diet on calcium and vitamin D status of periparturient cows and their calves.. Journal of dairy science, 98 ((8)): (5588-5600). [PMID:26051311]
45. Anna K Coussens,Celeste E Naude,Rene Goliath,George Chaplin,Robert J Wilkinson,Nina G Jablonski. (2015-06-17) High-dose vitamin D3 reduces deficiency caused by low UVB exposure and limits HIV-1 replication in urban Southern Africans.. Proceedings of the National Academy of Sciences of the United States of America, 112 ((26)): (8052-8057). [PMID:26080414]
46. O Bruyère,R Deroisy,N Dardenne,E Cavalier,M Coffiner,S Da Silva,S De Niet,J-Y Reginster. (2015-06-24) A phase IV, two-armed, randomized, cross-over study comparing compliance with once-a-month administration of vitamin D3 to compliance with daily administration of a fixed-dose combination of vitamin D3 and calcium during two 6-month periods.. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 26 ((12)): (2863-2868). [PMID:26100413]
47. Gloria Manzotti,Sandra Parenti,Giovanna Ferrari-Amorotti,Angela Rachele Soliera,Sara Cattelani,Monica Montanari,Daniel Cavalli,Adam Ertel,Alexis Grande,Bruno Calabretta. (2015-06-24) Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database.. Cell cycle (Georgetown, Tex.), 14 ((16)): (2578-2589). [PMID:26102293]
48. Bao-Xin Liu,Shu-Peng Chen,Yu-Dong Li,Ji Wang,Bin Zhang,Ying Lin,Jun-Hui Guan,Ying-Feng Cai,Zhu Liang,Fang Zheng. (2015-06-25) The Effect of the Modified Eighth Section of Eight-Section Brocade on Osteoporosis in Postmenopausal Women: A Prospective Randomized Trial.. Medicine, 94 ((25)): (e991-e991). [PMID:26107684]
49. Maria J Ramalho,Joana A Loureiro,Bárbara Gomes,Manuela F Frasco,Manuel A N Coelho,M Carmo Pereira. (2015-07-23) PLGA nanoparticles as a platform for vitamin D-based cancer therapy.. Beilstein journal of nanotechnology, 6 (1306-1318). [PMID:26199834]
50. Bassem Refaat,Adel Galal El-Shemi,Osama Adnan Kensara,Amr Mohamed Mohamed,Shakir Idris,Jawwad Ahmad,Athar Khojah. (2015-07-25) Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer.. Journal of experimental & clinical cancer research : CR, 34 (71-71). [PMID:26205949]
51. Li-hong Gao,Wen-jun Zhu,Yu-juan Liu,Jie-mei Gu,Zhen-lin Zhang,Ou Wang,Xiao-ping Xing,Ling Xu. (2015-08-19) Physical performance and life quality in postmenopausal women supplemented with vitamin D: a two-year prospective study.. Acta pharmacologica Sinica, 36 ((9)): (1065-1073). [PMID:26279157]
52. Lara Coelho,Sandra W Cardoso,Paula M Luz,Risa M Hoffman,Laura Mendonça,Valdilea G Veloso,Judith S Currier,Beatriz Grinsztejn,Jordan E Lake. (2015-08-19) Vitamin D3 supplementation in HIV infection: effectiveness and associations with antiretroviral therapy.. Nutrition journal, 14 (81-81). [PMID:26283663]
53. Ling-Hong Miao,Jun Xie,Xian-Ping Ge,Ke-Bao Wang,Jian Zhu,Bo Liu,Ming-Chun Ren,Qun-Lan Zhou,Liang-Kun Pan. (2015-09-13) Chronic stress effects of high doses of vitamin D3 on Megalobrama amblycephala.. Fish & shellfish immunology, 47 ((1)): (205-213). [PMID:26362210]
54. Zhaoke Wu,Ting Wang,Shenshen Zhu,Ling Li. (2015-10-07) Effects of vitamin D supplementation as an adjuvant therapy in coronary artery disease patients.. Scandinavian cardiovascular journal : SCJ, 50 ((1)): (9-16). [PMID:26440923]
55. Zaidoon Al-Jaderi,Azzam A Maghazachi. (2015-11-19) Vitamin D₃ and monomethyl fumarate enhance natural killer cell lysis of dendritic cells and ameliorate the clinical score in mice suffering from experimental autoimmune encephalomyelitis.. Toxins, 7 ((11)): (4730-4744). [PMID:26580651]
56. Rajesh A Maheshwari,Falak Dhakwala,R Balaraman,Avinash K Seth,Hardik Soni,Ghanshyam Patel. (2015-11-26) Maxcal-C (a polyherbal formulation) prevents ovariectomy-induced osteoporosis in rats.. Indian journal of pharmacology, 47 ((5)): (555-559). [PMID:26600648]
57. Umon Agata,Jong-Hoon Park,Satoshi Hattori,Yuki Aikawa,Yuya Kakutani,Ikuko Ezawa,Takayuki Akimoto,Naomi Omi. (2015-12-08) The Impact of Different Amounts of Calcium Intake on Bone Mass and Arterial Calcification in Ovariectomized Rats.. Journal of nutritional science and vitaminology, 61 ((5)): (391-399). [PMID:26639847]
58. Mr Baghaban Eslaminejad,S Vahabi,M Shariati,H Nazarian. (2011-10-15) In vitro Growth and Characterization of Stem Cells from Human Dental Pulp of Deciduous Versus Permanent Teeth.. Journal of dentistry (Tehran, Iran), 7 ((4)): (185-195). [PMID:21998794]
59. S Lopa,A Colombini,D Stanco,L de Girolamo,V Sansone,M Moretti. (2014-04-25) Donor-matched mesenchymal stem cells from knee infrapatellar and subcutaneous adipose tissue of osteoarthritic donors display differential chondrogenic and osteogenic commitment.. European cells & materials, 27 (298-311). [PMID:24760577]
60. M Rauner,U Föger-Samwald,M F Kurz,C Brünner-Kubath,D Schamall,A Kapfenberger,P Varga,S Kudlacek,A Wutzl,H Höger,P K Zysset,G P Shi,L C Hofbauer,W Sipos,P Pietschmann. (2014-05-02) Cathepsin S controls adipocytic and osteoblastic differentiation, bone turnover, and bone microarchitecture.. Bone, 64 (281-287). [PMID:24780878]
61. Luca De Toni,Vincenzo De Filippis,Simone Tescari,Marco Ferigo,Alberto Ferlin,Valentina Scattolini,Angelo Avogaro,Roberto Vettor,Carlo Foresta. (2014-08-06) Uncarboxylated osteocalcin stimulates 25-hydroxy vitamin D production in Leydig cell line through a GPRC6a-dependent pathway.. Endocrinology, 155 ((11)): (4266-4274). [PMID:25093461]
62. Sudhindra M Bhattacharya,Mainak Ghosh. (2014-12-09) Changes in serum calcium and vitamin D₃ levels after tibolone treatment and their correlations with health-related quality of life.. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 128 ((2)): (174-176). [PMID:25482436]
63. Bing Li,Qing Shao,Dong Ji,Fan Li,Guofeng Chen. (2015-01-24) Mesenchymal stem cells mitigate cirrhosis through BMP7.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 35 ((2)): (433-440). [PMID:25613158]
64. Lei Wang,Sebastian S DeMarco,JianMing Chen,Charles M Phillips,Lance C Bridges. (2015-04-01) Retinoids Bias Integrin Expression and Function in Cutaneous T-Cell Lymphoma.. The Journal of investigative dermatology, 135 ((8)): (2102-2108). [PMID:25826424]
65. Li-Shu Guo,Hong-Xia Li,Chun-Yang Li,Sheng-Yan Zhang,Jia Chen,Qi-Long Wang,Jing-Miao Gao,Jia-Qi Liang,Ming-Tang Gao,Yong-Jie Wu. (2015-05-23) Vitamin D3 enhances antitumor activity of metformin in human bladder carcinoma SW-780 cells.. Die Pharmazie, 70 ((2)): (123-128). [PMID:25997253]
66. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong. (2011-12-24) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).. PLoS computational biology, 7 ((12)): (e1002310-e1002310). [PMID:22194678]
67. Jian-Zhuang Tan,Yu-Ming Guo,Todd J Applegate,En-Cun Du,Xu Zhao. (2014-04-15) Dietary L-arginine modulates immunosuppression in broilers inoculated with an intermediate strain of infectious bursa disease virus.. Journal of the science of food and agriculture, 95 ((1)): (126-135). [PMID:24728981]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.