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VTP-27999 , CAS No.942142-51-0
Basic Description
Synonyms | 942142-51-0 | VTP-27999 | Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate | VTP27999 | VTP 27999 | methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3 |
Biochemical and Physiological Mechanisms |
VTP-27999 is an Alkyl Amine Renin Inhibitor. VTP-27999 is useful for Hypertension and End-Organ Diseases . |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
IUPAC Name | methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate |
INCHI | InChI=1S/C26H41ClN4O5/c1-28-23(14-19-6-5-12-35-18-19)16-30-25(32)31-11-4-8-21(17-31)24(20-7-3-9-22(27)15-20)36-13-10-29-26(33)34-2/h3,7,9,15,19,21,23-24,28H,4-6,8,10-14,16-18H2,1-2H3,(H,29,33)(H,30,32)/t19-,21-,23+,24+/m1/s1 |
InChi Key | NXWASIVXQMMPLM-ZXMXYHOLSA-N |
Canonical SMILES | CNC(CC1CCCOC1)CNC(=O)N2CCCC(C2)C(C3=CC(=CC=C3)Cl)OCCNC(=O)OC |
Isomeric SMILES | CN[C@@H](C[C@H]1CCCOC1)CNC(=O)N2CCC[C@H](C2)[C@H](C3=CC(=CC=C3)Cl)OCCNC(=O)OC |
PubChem CID | 16126898 |
Molecular Weight | 525.08 |
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Chemical and Physical Properties
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