VU0119498 - ≥99%, high purity , CAS No.79183-37-2, Allosteric modulator of M 1 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 5 receptor

Item Number
V275294
Grouped product items
SKUSizeAvailabilityPrice Qty
V275294-50mg
50mg
In stock
$157.90
V275294-250mg
250mg
In stock
$711.90
V275294-1g
1g
In stock
$2,559.90

M 1 muscarinic receptor agonist and pan mAChR M 3 , M 5 PAM

Basic Description

Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsM 1 muscarinic receptor agonist (EC 50 = 3.1 μM) and pan mAChR M 3 , M 5 positive allosteric modulator (PAM). Neuroprotective agent. Active in vitro .
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of M 1 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 5 receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. The product can be stored for up to 12 months.

Associated Targets(Human)

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-[(4-bromophenyl)methyl]indole-2,3-dione
INCHI InChI=1S/C15H10BrNO2/c16-11-7-5-10(6-8-11)9-17-13-4-2-1-3-12(13)14(18)15(17)19/h1-8H,9H2
InChi Key DELLOEULSHGYCG-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC=C(C=C3)Br
Isomeric SMILES C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC=C(C=C3)Br
PubChem CID 3008304
Molecular Weight 316.15

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
G2213415Certificate of AnalysisApr 18, 2023 V275294
G2213058Certificate of AnalysisApr 18, 2023 V275294
G2213059Certificate of AnalysisApr 18, 2023 V275294

Chemical and Physical Properties

SolubilitySoluble in DMSO to 100 mM

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P264:Wash hands [and …] thoroughly after handling.

P362:Take off contaminated clothing.

P337+P313:IF eye irritation persists: Get medical advice/attention.

P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

Related Documents

Solution Calculators