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WF-47-JS03 , CAS No.W614841, Inhibitor of ret proto-oncogene
Basic Description
Synonyms | compound 1 [Mathison et al., 2020];WF47JS03 |
Specifications & Purity | Moligand™ |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of ret proto-oncogene |
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Associated Targets(Human)
Mechanisms of Action
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
IUPAC Name | 3-(3,4-dimethoxyphenyl)-N5-(1,2,2,6,6-pentamethylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine |
INCHI | InChI=1S/C30H38N6O2/c1-29(2)16-21(17-30(3,4)35(29)5)33-27-25(19-11-9-8-10-12-19)26(31)36-28(34-27)22(18-32-36)20-13-14-23(37-6)24(15-20)38-7/h8-15,18,21H,16-17,31H2,1-7H3,(H,33,34) |
InChi Key | YRBWLEAMGAGYBK-UHFFFAOYSA-N |
Canonical SMILES | COc1cc(ccc1OC)c1cnn2c1nc(NC1CC(C)(C)N(C(C1)(C)C)C)c(c2N)c1ccccc1 |
Isomeric SMILES | CC1(CC(CC(N1C)(C)C)NC2=NC3=C(C=NN3C(=C2C4=CC=CC=C4)N)C5=CC(=C(C=C5)OC)OC)C |
PubChem CID | 145996543 |
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