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WJYK50 , CAS No.W614848, Inhibitor of sphingomyelin phosphodiesterase 1

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WJYK50 , CAS No.W614848, Inhibitor of sphingomyelin phosphodiesterase 1

Moligand™

PubChem CID: 145954576

Item Number

W614848

Grouped product items
SKU	Size	Availability	Price	Qty
W614848-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$560.90
W614848-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,500.90

View related series

sphingomyelin phosphodiesterase 1 Inhibitor

Basic Description

Synonyms	compound 1c
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of sphingomyelin phosphodiesterase 1

Associated Targets(Human)

SMPD1 Tchem Sphingomyelin phosphodiesterase (3 Activities)

Discover Target: SMPD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMPD2 Tchem Neutral sphingomyelinase (40 Activities)

Discover Target: SMPD2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)

Discover Target: SMPD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(Decyloxy)-N-hydroxy-4-methoxybenzamide
INCHI	InChI=1S/C18H29NO4/c1-3-4-5-6-7-8-9-10-13-23-17-14-15(18(20)19-21)11-12-16(17)22-2/h11-12,14,21H,3-10,13H2,1-2H3,(H,19,20)
InChi Key	QKPYTKNEFFAFOV-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCOc1cc(ccc1OC)C(=O)NO
Isomeric SMILES	CCCCCCCCCCOC1=C(C=CC(=C1)C(=O)NO)OC
PubChem CID	145954576

Database links

PubChem CID	145954576

Certificates

Certificate of Analysis(COA)

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References

1. Yang K, Nong K, Gu Q, Dong J, Wang J. (2018) Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model.. Eur J Med Chem, 151 (13): (389-400). [PMID:29649738] [10.1021/op500134e]

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