Wnt10b Antibody - Primary antibody, specific to WNT10B, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab134730
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab134730-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$96.90
Ab134730-50μl
50μl
In stock
$279.90
Ab134730-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$409.90
Ab134730-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

pAb; Rabbit anti Human Wnt10b Antibody; WB; Unconjugated

Basic Description

Product NameWnt10b Antibody - Primary antibody, specific to WNT10B, Rabbit IgG
SynonymsProtein Wnt-10b antibody | Protein Wnt-12 antibody | SHFM6 antibody | wingless type MMTV integration site family, member 10B antibody | WN10B_HUMAN antibody | WNT 10B protein antibody | WNT 12 antibody | Wnt10b antibody | wnt12 antibody | protein Wnt-10b
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, 0.5 mg/mL
Host speciesRabbit
SpecificityWNT10B
ImmunogenA KLH conjugated synthetic peptide from the Central region of human WNT10B (AA 193-222).
Positive ControlWB: Mouse skeletal muscle, HeLa, Hep G2, MDA-MB-231 and HT-29 cell lysates.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human Wnt10b Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 1/2000
Protein Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified + Peptide affinity purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Wnt10b Antibody (Ab134730) - Western Blot
All lanes: Wnt10b Antibody (Ab134730) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 43 kDa
Observed band size: 39, 46 kDa
Exposure time: 73.7 s

Associated Targets(Human)

WNT10B Tbio Protein Wnt-10b (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB1/2000

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1/2000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ23F1202103Certificate of AnalysisDec 19, 2023 Ab134730
ZJ23F1202102Certificate of AnalysisDec 19, 2023 Ab134730

Related Documents

References

1. Bui, T D TD and 7 more authors..  (1997)  A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas..  Oncogene,    (13):   [PMID:9121776]
2. Hardiman, G G, Kastelein, R A RA and Bazan, J F JF..  (1997)  Isolation, characterization and chromosomal localization of human WNT10B..  Cytogenetics and cell genetics,      [PMID:9284937]
3. Bergstein, I I and 7 more authors..  (1997)  Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21..  Genomics,    (15):   [PMID:9441749]
4. Saitoh, T T, Kirikoshi, H H, Mine, T T and Katoh, M M..  (2001)  Proto-oncogene WNT10B is up-regulated by tumor necrosis factor alpha in human gastric cancer cell line MKN45..  International journal of oncology,      [PMID:11713588]
5. Christodoulides, C C and 14 more authors..  (2006)  WNT10B mutations in human obesity..  Diabetologia,      [PMID:16477437]
6. Scherer, Steven E SE and 216 more authors..  (2006)  The finished DNA sequence of human chromosome 12..  Nature,    (16):   [PMID:16541075]
7. Ugur, Sibel Aylin SA and Tolun, Aslihan A..  (2008)  Homozygous WNT10b mutation and complex inheritance in Split-Hand/Foot Malformation..  Human molecular genetics,    (1):   [PMID:18515319]
8. Wend, P P, Wend, K K, Krum, S A SA and Miranda-Carboni, G A GA..  (2012)  The role of WNT10B in physiology and disease..  Acta physiologica (Oxford, England),      [PMID:21447090]
9. Mihara, Emiko E and 7 more authors..  (2016)  Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin..  eLife,    (23):   [PMID:26902720]
10. Yu, Ping P and 15 more authors..  (2016)  Mutations in WNT10B Are Identified in Individuals with Oligodontia..  American journal of human genetics,    (7):   [PMID:27321946]

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