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WWL 123 - ≥98%(HPLC), high purity , CAS No.1338574-83-6
α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic
Basic Description Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50= 0.43μM). BlocksPTZ-induced seizures in healthy mice and spontaneous seizures in R6/2 mice. Antiepileptic activity is independent of CB1and CB2receptors, but is GABAAreceptor dependent. Brain penetrant. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name [4-(4-carbamoylphenyl)phenyl] N-methyl-N-[(3-phenylphenyl)methyl]carbamate INCHI InChI=1S/C28H24N2O3/c1-30(19-20-6-5-9-25(18-20)21-7-3-2-4-8-21)28(32)33-26-16-14-23(15-17-26)22-10-12-24(13-11-22)27(29)31/h2-18H,19H2,1H3,(H2,29,31) InChi Key UUJGYRHAOHORFC-UHFFFAOYSA-N Canonical SMILES CN(CC1=CC(=CC=C1)C2=CC=CC=C2)C(=O)OC3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)N Isomeric SMILES CN(CC1=CC(=CC=C1)C2=CC=CC=C2)C(=O)OC3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)N PubChem CID 90209976 Molecular Weight 436.5
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 43.65, Max Conc. mM: 100
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G23261168