WWL 70 - ≥98%(HPLC), high purity , CAS No.947669-91-2, Inhibitor of αβ-Hydrolase 6

Item Number
W288650
Grouped product items
SKUSizeAvailabilityPrice Qty
W288650-1mg
1mg
In stock
$28.90
W288650-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$116.90
W288650-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$182.90
W288650-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$365.90
W288650-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$626.90
W288650-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$888.90

Potent ABHD6 inhibitor

View related series
αβ-Hydrolase 6 Inhibitor

Basic Description

Synonyms4'-Carbamoyl-[1,1'-biphenyl]-4-yl methyl(3-(pyridin-4-yl)benzyl)carbamate | WWL70, >=98% (HPLC) | WWL 70 | EX-A2937 | DTXSID40590859 | XMB66991 | 4'-Carbamoylbiphenyl-4-yl methyl(3-(pyridin-4-yl)benzyl)carbamate | AKOS024457508 | GTPL5289 | MS-27841 | SCH
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsPotent inhibitor ofα/β-hydrolase domain 6 (ABHD6) (IC50= 70 nM), an enzyme which catalyzes the hydrolysis of2-arachidonylglycerol.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of αβ-Hydrolase 6

Associated Targets(Human)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MGLL Tchem Monoglyceride lipase (1909 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABHD12 Tchem Monoacylglycerol lipase ABHD12 (195 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abhd6 Monoacylglycerol lipase ABHD6 (221 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [4-(4-carbamoylphenyl)phenyl] N-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate
INCHI InChI=1S/C27H23N3O3/c1-30(18-19-3-2-4-24(17-19)22-13-15-29-16-14-22)27(32)33-25-11-9-21(10-12-25)20-5-7-23(8-6-20)26(28)31/h2-17H,18H2,1H3,(H2,28,31)
InChi Key QTWNORFUQILKJL-UHFFFAOYSA-N
Canonical SMILES CN(CC1=CC(=CC=C1)C2=CC=NC=C2)C(=O)OC3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)N
Isomeric SMILES CN(CC1=CC(=CC=C1)C2=CC=NC=C2)C(=O)OC3=CC=C(C=C3)C4=CC=C(C=C4)C(=O)N
PubChem CID 17759121
Molecular Weight 437.49

Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
A2304162Certificate of AnalysisJul 29, 2022 W288650
K2222516Certificate of AnalysisJul 29, 2022 W288650
K2223513Certificate of AnalysisJul 29, 2022 W288650
K2223514Certificate of AnalysisJul 29, 2022 W288650
K2223515Certificate of AnalysisJul 29, 2022 W288650
K2223517Certificate of AnalysisJul 29, 2022 W288650
K2223518Certificate of AnalysisJul 29, 2022 W288650

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 4.37, Max Conc. mM: 10

Safety and Hazards(GHS)

RIDADR NONHforallmodesoftransport

Related Documents

Solution Calculators