WZB 117 - 98%, high purity , CAS No.1223397-11-2

  • ≥98%
Item Number
W287116
Grouped product items
SKUSizeAvailabilityPrice Qty
W287116-5mg
5mg
In stock
$53.90
W287116-10mg
10mg
In stock
$86.90
W287116-25mg
25mg
In stock
$173.90
W287116-50mg
50mg
In stock
$282.90
W287116-100mg
100mg
In stock
$509.90
W287116-200mg
200mg
In stock
$916.90

GLUT inhibitor

Basic Description

SynonymsWZB117 | 1223397-11-2 | 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate) | WZB 117 | WZB-117 | CHEMBL3092944 | [3-fluoro-2-(3-hydroxybenzoyl)oxyphenyl] 3-hydroxybenzoate | Benzoic acid, 3-hydroxy-, 1,1'-(3-fluoro-1,2-phenylene) ester | SCHEMBL19183300 | BCP24665 | EX-A1492 | BDBM
Specifications & Purity≥98%
Biochemical and Physiological MechanismsGLUT inhibitor (Ki(app)values are 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively). Competitive inhibitor of net glucose uptake but a noncompetitive inhibitor of sugar efflux from cells. Inhibits passive sugar transport in human erythrocytes an
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

SLC2A1 Tchem Glucose transporter (14755 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H1299 (3248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC2A3 Tchem Solute carrier family 2, facilitated glucose transporter member 3 (465 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC2A2 Tchem Solute carrier family 2, facilitated glucose transporter member 2 (428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC2A4 Tchem Solute carrier family 2, facilitated glucose transporter member 4 (396 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488201362
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488201362
IUPAC Name [3-fluoro-2-(3-hydroxybenzoyl)oxyphenyl] 3-hydroxybenzoate
INCHI InChI=1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
InChi Key FRSWCCBXIHFKKY-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
Isomeric SMILES C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
WGK Germany 3
PubChem CID 46830365
Molecular Weight 368.31

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
C23281027Certificate of AnalysisJan 05, 2023 W287116
C23281028Certificate of AnalysisJan 05, 2023 W287116
C23281029Certificate of AnalysisJan 05, 2023 W287116
C23281030Certificate of AnalysisJan 05, 2023 W287116
C23281031Certificate of AnalysisJan 05, 2023 W287116
C23281032Certificate of AnalysisJan 05, 2023 W287116
C23281033Certificate of AnalysisJan 05, 2023 W287116
C23281034Certificate of AnalysisJan 05, 2023 W287116
C23281035Certificate of AnalysisJan 05, 2023 W287116
C23281036Certificate of AnalysisJan 05, 2023 W287116
C23281038Certificate of AnalysisJan 05, 2023 W287116
C2328624Certificate of AnalysisJan 05, 2023 W287116

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 36.83, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 36.83, Max Conc. mM: 100

Safety and Hazards(GHS)

WGK Germany 3
RIDADR NONHforallmodesoftransport

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Solution Calculators