WZB 117 - 10mM in DMSO, high purity , CAS No.1223397-11-2

Item Number

W420962

Grouped product items
SKU	Size	Availability	Price	Qty
W420962-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$241.90

GLUT inhibitor

Basic Description

Synonyms	WZB117 \| 1223397-11-2 \| 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate) \| WZB 117 \| WZB-117 \| CHEMBL3092944 \| [3-fluoro-2-(3-hydroxybenzoyl)oxyphenyl] 3-hydroxybenzoate \| Benzoic acid, 3-hydroxy-, 1,1'-(3-fluoro-1,2-phenylene) ester \| SCHEMBL19183300 \| BCP24665 \| EX-A1492 \| BDBM
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	GLUT inhibitor (Ki(app)values are 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively). Competitive inhibitor of net glucose uptake but a noncompetitive inhibitor of sugar efflux from cells. Inhibits passive sugar transport in human erythrocytes an
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

SLC2A1 Tchem Glucose transporter (14755 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H1299 (3248 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC2A3 Tchem Solute carrier family 2, facilitated glucose transporter member 3 (465 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC2A2 Tchem Solute carrier family 2, facilitated glucose transporter member 2 (428 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC2A4 Tchem Solute carrier family 2, facilitated glucose transporter member 4 (396 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[3-fluoro-2-(3-hydroxybenzoyl)oxyphenyl] 3-hydroxybenzoate
INCHI	InChI=1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
InChi Key	FRSWCCBXIHFKKY-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
Isomeric SMILES	C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
WGK Germany	3
PubChem CID	46830365
Molecular Weight	368.31

WGK Germany

RIDADR

NONHforallmodesoftransport

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Basic Description