XD14 - 95%, high purity , CAS No.1370888-71-3, Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4;Inhibitor of bromodomain testis associated
XD14 - 95%, high purity , CAS No.1370888-71-3, Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4;Inhibitor of bromodomain testis associated
XD14 is an inhibitor of BET bromodomain with Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd of 1.2 μM, 1.6 μM, 2.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4;Inhibitor of bromodomain testis associated
Product Description
Information
XD14 is an inhibitor of BET bromodomain with Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd of 1.2 μM, 1.6 μM, 2.6 μM and 3.7 μM, respectively.
Associated Targets(Human)
BRD4TchemBromodomain-containing protein 4 (3 Activities)
