XY1 - 98%, high purity , CAS No.1624117-53-8

  • ≥98%
Item Number
X412226
Grouped product items
SKUSizeAvailabilityPrice Qty
X412226-1mg
1mg
In stock
$15.90
X412226-5mg
5mg
In stock
$63.90
X412226-10mg
10mg
In stock
$107.90
X412226-25mg
25mg
In stock
$243.90
X412226-50mg
50mg
In stock
$385.90
X412226-100mg
100mg
In stock
$642.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsXY1 is an analog of SGC707 (SGC707 is a potent and selective PRMT3 inhibitor with IC50 of 31 nM), but XY1 is completely inactive against PRMT3.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

XY1 is an inactive, close analog of SGC707 that can be used as the negative control for SGC707. SGC707 is a potent, selective and cell-active allosteric inhibitor ofprotein arginine methyltransferase 3 (PRMT3)with IC50 and Kd of 31 nM and 53 nM, respectively.

Associated Targets(Human)

PRMT3 Tchem Protein arginine N-methyltransferase 3 (219 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
INCHI InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)
InChi Key GSQHGSRPQHBTTP-UHFFFAOYSA-N
Canonical SMILES C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
Isomeric SMILES C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
PubChem CID 78871801
Molecular Weight 297.35

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
J2214494Certificate of AnalysisJul 09, 2024 X412226
J2214459Certificate of AnalysisJul 09, 2024 X412226
J2214780Certificate of AnalysisJul 08, 2024 X412226
J2214819Certificate of AnalysisJul 08, 2024 X412226
J2214820Certificate of AnalysisJul 08, 2024 X412226
J2214821Certificate of AnalysisJul 08, 2024 X412226

Chemical and Physical Properties

SolubilityDMSO : 67.5 mg/mL (227.01 mM)

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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