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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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X412226-1mg | 1mg | In stock | $15.90 | |
X412226-5mg | 5mg | In stock | $63.90 | |
X412226-10mg | 10mg | In stock | $107.90 | |
X412226-25mg | 25mg | In stock | $243.90 | |
X412226-50mg | 50mg | In stock | $385.90 | |
X412226-100mg | 100mg | In stock | $642.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | XY1 is an analog of SGC707 (SGC707 is a potent and selective PRMT3 inhibitor with IC50 of 31 nM), but XY1 is completely inactive against PRMT3. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information XY1 is an inactive, close analog of SGC707 that can be used as the negative control for SGC707. SGC707 is a potent, selective and cell-active allosteric inhibitor ofprotein arginine methyltransferase 3 (PRMT3)with IC50 and Kd of 31 nM and 53 nM, respectively. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea |
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INCHI | InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22) |
InChi Key | GSQHGSRPQHBTTP-UHFFFAOYSA-N |
Canonical SMILES | C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2 |
Isomeric SMILES | C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2 |
PubChem CID | 78871801 |
Molecular Weight | 297.35 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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J2214494 | Certificate of Analysis | Jul 09, 2024 | X412226 |
J2214459 | Certificate of Analysis | Jul 09, 2024 | X412226 |
J2214780 | Certificate of Analysis | Jul 08, 2024 | X412226 |
J2214819 | Certificate of Analysis | Jul 08, 2024 | X412226 |
J2214820 | Certificate of Analysis | Jul 08, 2024 | X412226 |
J2214821 | Certificate of Analysis | Jul 08, 2024 | X412226 |
Solubility | DMSO : 67.5 mg/mL (227.01 mM) |
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Signal | Warning |
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Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |