XY101 - 98%, high purity , CAS No.2349368-16-5

Item Number

X650499

• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC 50 of 30 nM and a K d of 380 nM.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC 50 of 30 nM and a K d of 380 nM

In Vitro

XY101 potently inhibits cell growth, colony formation, and the expression of androgen receptor (AR), AR-V7 and prostate-specific antigen (PSA). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 30 nM (RORγ), Kd: 380 nM (RORγ)