Basic Description

Synonyms	AS-80369 \| A899245 \| 1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis- \| YM 26734 \| F90262 \| YM26734 \| YM-26734 \| NCGC00387064-05 \| 1-{3-Dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4
Specifications & Purity	≥95%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Product Description： YM-26734 is a rabbit platelet sPLA2 inhibitor that has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema.

Associated Targets(Human)

PLA2G10 Tchem Group 10 secretory phospholipase A2 (1 Activities)

Discover Target: PLA2G10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2A Tchem Phospholipase A2, membrane associated (2 Activities)

Discover Target: PLA2G2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G5 Tchem Calcium-dependent phospholipase A2 (1 Activities)

Discover Target: PLA2G5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)

Discover Target: PLA2G2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G10 Tchem Group X secretory phospholipase A2 (219 Activities)

Discover Target: PLA2G10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G5 Tchem Phospholipase A2 group V (238 Activities)

Discover Target: PLA2G5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
INCHI	InChI=1S/C45H62O8/c1-3-5-7-9-11-13-15-17-19-21-36(48)41-43(50)40(44(51)42(45(41)52)37(49)22-20-18-16-14-12-10-8-6-4-2)35-30-38(31-23-25-32(46)26-24-31)53-39-29-33(47)27-28-34(35)39/h23-29,35,38,46-47,50-52H,3-22,30H2,1-2H3
InChi Key	CEJAYJCUSZHYDS-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCCC(=O)C1=C(C(=C(C(=C1O)C2CC(OC3=C2C=CC(=C3)O)C4=CC=C(C=C4)O)O)C(=O)CCCCCCCCCCC)O
Isomeric SMILES	CCCCCCCCCCCC(=O)C1=C(C(=C(C(=C1O)C2CC(OC3=C2C=CC(=C3)O)C4=CC=C(C=C4)O)O)C(=O)CCCCCCCCCCC)O
PubChem CID	9853400
Molecular Weight	730.97

Certificates

Certificate of Analysis(COA)

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1 results found

Lot Number	Certificate Type	Date	Item
K2108801	Certificate of Analysis	Aug 20, 2024	Y288422

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 73.1, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 73.1, Max Conc. mM: 100

Safety and Hazards(GHS)

RIDADR	NONHforallmodesoftransport

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YM 26734 - ≥95%(HPLC), high purity , CAS No.144337-18-8