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YM201636 - 96%, high purity , CAS No.371942-69-7
Basic Description Synonyms 371942-69-7 | YM201636 | YM-201636 | YM 201636 | 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide | 3-pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]- | CHEM Specifications & Purity ≥96% Biochemical and Physiological Mechanisms YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain. YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM). binds Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488196470 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488196470 IUPAC Name 6-amino-N-[3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenyl]pyridine-3-carboxamide INCHI InChI=1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17)22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8,13-14H,9-12H2,(H2,26,28)(H,29,33) InChi Key YBPIBGNBHHGLEB-UHFFFAOYSA-N Canonical SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N Isomeric SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N PubChem CID 9956222 Molecular Weight 467.48
Chemical and Physical Properties Solubility DMSO 35 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
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E2316808