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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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Y412930-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,740.90 | |
Y412930-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,782.90 | |
Y412930-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,823.90 | |
Y412930-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $219.90 | |
Y412930-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,065.90 | |
Y412930-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,275.90 |
Synonyms | 4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester; Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | YMU1 is an inhibitor of human thymidylate kinase (hTMPK). YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | YMU1 is a selective inhibitor of human thymidylate kinase (hTMPK) with an IC50 of 610 nM |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | ethyl 4-[2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)acetyl]piperazine-1-carboxylate |
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INCHI | InChI=1S/C17H22N4O4S/c1-4-25-17(24)20-7-5-19(6-8-20)13(22)10-21-16(23)14-11(2)9-12(3)18-15(14)26-21/h9H,4-8,10H2,1-3H3 |
InChi Key | XXUFNNVFZFVKGP-UHFFFAOYSA-N |
Canonical SMILES | CCOC(=O)N1CCN(CC1)C(=O)CN2C(=O)C3=C(S2)N=C(C=C3C)C |
Isomeric SMILES | CCOC(=O)N1CCN(CC1)C(=O)CN2C(=O)C3=C(S2)N=C(C=C3C)C |
WGK Germany | 3 |
PubChem CID | 49878590 |
Molecular Weight | 378.45 |
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Lot Number | Certificate Type | Date | Item |
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B2421085 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421086 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421087 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421088 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421089 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421090 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421091 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421092 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421093 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421094 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421095 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
B2421096 | Certificate of Analysis | Jan 10, 2024 | Y412930 |
Solubility | Chloroform: 30 mg/ml,DMF: 0.30 mg/mL |
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WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |