The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
YQ128 - 10mM in DMSO, high purity , CAS No.2454246-18-3(DMSO)
Basic Description Specifications & Purity 10mM in DMSO Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description Product description：
YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM. YQ128 significantly and selectively suppresses the production of IL-1β, but not TNF-α, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name N-[(5-chloro-2-propoxyphenyl)methyl]-N-[2-[4-(prop-2-ynylsulfamoyl)phenyl]ethyl]-2-thiophen-3-ylacetamide INCHI InChI=1S/C27H29ClN2O4S2/c1-3-13-29-36(32,33)25-8-5-21(6-9-25)11-14-30(27(31)17-22-12-16-35-20-22)19-23-18-24(28)7-10-26(23)34-15-4-2/h1,5-10,12,16,18,20,29H,4,11,13-15,17,19H2,2H3 InChi Key SFPYRFRNYALLHS-UHFFFAOYSA-N Canonical SMILES CCCOC1=C(C=C(C=C1)Cl)CN(CCC2=CC=C(C=C2)S(=O)(=O)NCC#C)C(=O)CC3=CSC=C3 Isomeric SMILES CCCOC1=C(C=C(C=C1)Cl)CN(CCC2=CC=C(C=C2)S(=O)(=O)NCC#C)C(=O)CC3=CSC=C3 PubChem CID 139600339 Molecular Weight 545.11
Chemical and Physical Properties Solubility DMSO：100mg/mL（183.45mM）；Ethanol: 3mg/mL (5.5mM)；H2O:insoluble
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
