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Z-DEVD-FMK - ≥98%, high purity , CAS No.210344-95-9

Specifications & Purity:  ≥98%
Item Number
Z302772
Grouped product items
SKUSizeAvailabilityPrice Qty
Z302772-1mg
1mg
In stock
$64.90
Z302772-5mg
5mg
In stock
$176.90
Z302772-10mg
10mg
In stock
$295.90
Z302772-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$666.90
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Discover Z-DEVD-FMK by Aladdin Scientific in ≥98% for only $64.90. Available - in Ligands at Aladdin Scientific. Cell permeable caspase-3 inhibitor Tags: .

Basic Description

SynonymsZ-DEVD-FMK|210344-95-9|Caspase-3 Inhibitor|C30H41FN4O12|benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone|L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InDry ice

Associated Targets

CASP3 Tchem Caspase-3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-5-oxopentanoate
INCHI InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
InChi Key GBJVAVGBSGRRKN-JYEBCORGSA-N
Canonical SMILES CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES CC(C)[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCC1=CC=CC=C1
PubChem CID 16760394
Molecular Weight 668.66

Certificates

Certificate of Analysis(COA)

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7 results found

Lot NumberCertificate TypeDateItem
C2306441Certificate of AnalysisNov 11, 2022 Z302772
C2306445Certificate of AnalysisNov 11, 2022 Z302772
C2306446Certificate of AnalysisNov 11, 2022 Z302772
C2306447Certificate of AnalysisNov 11, 2022 Z302772
C2401077Certificate of AnalysisNov 11, 2022 Z302772
C2427089Certificate of AnalysisNov 11, 2022 Z302772
L2327024Certificate of AnalysisNov 11, 2022 Z302772

Chemical and Physical Properties

Solubilityinsoluble in H2O; insoluble in EtOH; ≥60 mg/mL in DMSO

Related Documents

 SDS

 Specification Sheet

FAQs and Articles

FAQ
PANoptosis: An inflammatory programmed cell death pathway
Categories: Technical articles
Tags:
PAN apoptosis

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References

1. De D et al..  (2019)  Ethanolic extract of leaf of Dillenia pentagyna reduces in-vitro cell migration and induces intrinsic pathway of apoptosis via downregulation of NF-?ß in human NSCLC A549 cells..  J Cell Biochem,  120  (12): (19841-19857).  [PMID:31318086]
2. Yang H et al..  (2019)  Qingjie Fuzheng granules inhibit colorectal cancer cell growth by the PI3K/AKT and ERK pathways..  World J Gastrointest Oncol,  11  (5): (377-392).  [PMID:31139308]

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