Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor. Selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Inhibits cathepsin B, L, and S, papain and cruzain. Induces apoptosis and necrosis.
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
1.Koike S et al.. (2016) Advanced Glycation End-Products Induce Apoptosis of Vascular Smooth Muscle Cells: A Mechanism for Vascular Calcification.. Int J Mol Sci, 17 (9):[PMID:27649164]
2.Harrison JS et al.. (2016) The role of VDR and BIM in potentiation of cytarabine-induced cell death in human AML blasts.. Oncotarget, 7 (24):(36447-36460). [PMID:27144333]
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