The store will not work correctly when cookies are disabled.
Z-VAD(OH)-FMK (Caspase Inhibitor VI) - 97%, high purity , CAS No.161401-82-7
Basic Description
| Synonyms | Z-Val-Ala-Asp fluoromethylketone | SCHEMBL17494194 | benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp fluoromethyl ketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl |
|---|
| Specifications & Purity | ≥97% |
|---|
| Biochemical and Physiological Mechanisms | Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor. |
|---|
| Storage Temp | Protected from light,Store at -20°C |
|---|
| Shipped In | Ice chest + Ice pads |
|---|
| Product Description | Information Z-VAD(OH)-FMK (Caspase Inhibitor VI) Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan- caspase inhibitor.
Targets Caspase
In vitro Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes. |
|---|
Product Properties
| ALogP | 1.246 |
|---|
| HBD Count | 3 |
|---|
| Rotatable Bond | 13 |
|---|
Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
| IUPAC Name | (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid |
|---|
| INCHI | InChI=1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1 |
|---|
| InChi Key | SUUHZYLYARUNIA-YEWWUXTCSA-N |
|---|
| Canonical SMILES | CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1 |
|---|
| Isomeric SMILES | C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1 |
|---|
| PubChem CID | 5497171 |
|---|
| Molecular Weight | 453.46 |
|---|
Chemical and Physical Properties
| Solubility | Solubility (25°C) In vitro DMSO: 90 mg/mL (198.47 mM); Ethanol: 90 mg/mL (198.47 mM); Water: Insoluble; |
|---|
| Sensitivity | Light sensitive ；Moisture sensitive |
|---|
| DMSO(mg / mL) Max Solubility | 90 |
|---|
| DMSO(mM) Max Solubility | 198.4739558 |
|---|
| Water(mg / mL) Max Solubility | ＜1 |
|---|
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
C2311666