Skip to the beginning of the images gallery

Z-VAD(OH)-FMK (Caspase Inhibitor VI) - 97%, high purity , CAS No.161401-82-7

≥97%

CAS#: 161401-82-7
Formula: C₂₁H₂₈FN₃O₇
Molecular Weight: 453.46
PubChem CID: 5497171

Item Number

Z413908

Grouped product items
SKU	Size	Availability	Price
Z413908-1mg	1mg	In stock	$144.90
Z413908-5mg	5mg	In stock	$305.90
Z413908-10mg	10mg	In stock	$520.90
Z413908-25mg	25mg	In stock	$1,172.90

Caspase Inhibitors

Basic Description

Synonyms	161401-82-7\|Caspase Inhibitor VI\|Z-VAD(OH)-FMK\|benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone\|Z-Val-Ala-Asp Fluoromethyl ketone\|Z-Val-Ala-Asp-CH2F\|L-alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-\|(3S)-5
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information Z-VAD(OH)-FMK (Caspase Inhibitor VI) Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan- caspase inhibitor. Targets Caspase In vitro Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes.

ALogP

1.246

HBD Count

Rotatable Bond

Associated Targets

CASP8 Tchem Caspase-8 0 Activities

Discover Target: CASP8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CASP1 Tchem Caspase-1 0 Activities

Discover Target: CASP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CASP3 Tchem Caspase-3 0 Activities

Discover Target: CASP3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CASP6 Tchem Caspase-6 0 Activities

Discover Target: CASP6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSDMD Tchem Gasdermin-D 0 Activities

Discover Target: GSDMD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid
INCHI	InChI=1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
InChi Key	SUUHZYLYARUNIA-YEWWUXTCSA-N
Canonical SMILES	CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1
PubChem CID	5497171
Molecular Weight	453.46

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
C2311666	Certificate of Analysis	Feb 23, 2023	Z413908
C2311667	Certificate of Analysis	Feb 23, 2023	Z413908
C2311669	Certificate of Analysis	Feb 23, 2023	Z413908
C2311713	Certificate of Analysis	Feb 23, 2023	Z413908

Solubility

Solubility (25°C) In vitro DMSO: 90 mg/mL (198.47 mM); Ethanol: 90 mg/mL (198.47 mM); Water: Insoluble;

Sensitivity

Light sensitive ；Moisture sensitive

DMSO(mg / mL) Max Solubility

DMSO(mM) Max Solubility

198.4739558

Water(mg / mL) Max Solubility

＜1

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.