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Z-VAD(OH)-FMK (Caspase Inhibitor VI) - 10mM in DMSO, high purity , CAS No.161401-82-7

10mM in DMSO

CAS#: 161401-82-7
Formula: C₂₁H₂₈FN₃O₇
Molecular Weight: 453.46
PubChem CID: 5497171

Item Number

Z421947

Grouped product items
SKU	Size	Availability	Price	Qty
Z421947-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$241.90

Caspase Inhibitors

Basic Description

Synonyms	161401-82-7 \| Caspase Inhibitor VI \| Z-VAD(OH)-FMK \| benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone \| Z-Val-Ala-Asp Fluoromethyl ketone \| Z-Val-Ala-Asp-CH2F \| L-alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- \| (3S)-5
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Information Z-VAD(OH)-FMK (Caspase Inhibitor VI) Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan- caspase inhibitor. Targets Caspase In vitro Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes.

ALogP

1.246

HBD Count

Rotatable Bond

Associated Targets(Human)

CASP3 Tchem Caspase-3 (3632 Activities)

Discover Target: CASP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CASP8 Tchem Caspase-8 (1006 Activities)

Discover Target: CASP8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CASP1 Tchem Caspase-1 (6235 Activities)

Discover Target: CASP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CASP6 Tchem Caspase-6 (1213 Activities)

Discover Target: CASP6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Huh-7 (12904 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SF-188 (17 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Jurkat (10389 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hep 3B2 (2332 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GSDMD Tchem Gasdermin-D (6 Activities)

Discover Target: GSDMD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid
INCHI	InChI=1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
InChi Key	SUUHZYLYARUNIA-YEWWUXTCSA-N
Canonical SMILES	CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1
PubChem CID	5497171
Molecular Weight	453.46

DMSO(mg / mL) Max Solubility

DMSO(mM) Max Solubility

198.4739558

Water(mg / mL) Max Solubility

＜1

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Z-VAD(OH)-FMK (Caspase Inhibitor VI) - 10mM in DMSO, high purity , CAS No.161401-82-7

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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