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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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Z287819-5mg | 5mg | In stock | $107.90 | |
Z287819-10mg | 10mg | In stock | $177.90 | |
Z287819-25mg | 25mg | In stock | $355.90 | |
Z287819-50mg | 50mg | In stock | $573.90 | |
Z287819-100mg | 100mg | In stock | $909.90 |
Highly potent 5-HT3antagonist; also 5-HT4agonist
Synonyms | HY-103137 | Q27274695 | (+/-)-4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride | 4-amino-n-1-azabicyclo[2,2,2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride | BEA30398 | DTXCID2025686 | MS-25317 | SR-01000597764-1 | Zaco |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Highly potent 5-HT3receptor antagonist (Ki= 0.38 nM) and 5-HT4receptor agonist (Ki= 373 nM). Antiemetic and anxiolytic following systemic administrationin vivo. |
Storage Temp | Store at 2-8°C,Desiccated |
Shipped In | Wet ice |
Product Description | Product description Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist with Kis of 0.38 and 373 nM for 5-HT3 and 5-HT4 receptor, respectively. Zacopride hydrochloride is also a moderate IK1 channel agonist. Zacopride hydrochloride exerts significant antiarrhythmic and cardiac protective effects。 |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Pubchem Sid | 488196440 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488196440 |
IUPAC Name | 4-amino-N-(1-azabicyclo[2.2.2]octan-3-yl)-5-chloro-2-methoxybenzamide;hydrochloride |
INCHI | InChI=1S/C15H20ClN3O2.ClH/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19;/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20);1H |
InChi Key | ITXVOUSORXSTQH-UHFFFAOYSA-N |
Canonical SMILES | COC1=CC(=C(C=C1C(=O)NC2CN3CCC2CC3)Cl)N.Cl |
Isomeric SMILES | COC1=CC(=C(C=C1C(=O)NC2CN3CCC2CC3)Cl)N.Cl |
PubChem CID | 9928181 |
Molecular Weight | 346.26 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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D2308665 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308668 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308670 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308686 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308701 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308702 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308703 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308706 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308707 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
D2308710 | Certificate of Analysis | Feb 20, 2023 | Z287819 |
Solubility | Solvent:water, Max Conc. mg/mL: 34.63, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 34.62, Max Conc. mM: 100 |
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Sensitivity | Moisture sensitive |