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ZD 9379 - ≥98%(HPLC), high purity , CAS No.170142-20-8

Item Number

Z287711

Grouped product items
SKU	Size	Availability	Price	Qty
Z287711-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$183.90

Brain penetrant NMDA antagonist; acts at glycine site

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Basic Description

Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	NMDA receptor antagonist; acts at glycine site. Neuroprotective; reduces infarct size and frequency of spreading depressions in a rat model of ischemic stroke. Brain penetrant.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice

ABCB11 Tchem Bile salt export pump (2311 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	7-chloro-2-(4-methoxy-2-methylphenyl)-3,5-dihydropyridazino[4,5-b]quinoline-1,4,10-trione
INCHI	InChI=1S/C19H14ClN3O4/c1-9-7-11(27-2)4-6-14(9)23-19(26)15-16(18(25)22-23)21-13-8-10(20)3-5-12(13)17(15)24/h3-8H,1-2H3,(H,21,24)(H,22,25)
InChi Key	PSTDMIAVUUYOOQ-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C=CC(=C1)OC)N2C(=O)C3=C(C(=O)N2)NC4=C(C3=O)C=CC(=C4)Cl
Isomeric SMILES	CC1=C(C=CC(=C1)OC)N2C(=O)C3=C(C(=O)N2)NC4=C(C3=O)C=CC(=C4)Cl
PubChem CID	9843028
Molecular Weight	383.79

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Solubility	Solvent:DMSO, Max Conc. mg/mL: 19.19, Max Conc. mM: 50; Solvent:1eq. NaOH, Max Conc. mg/mL: 7.68, Max Conc. mM: 20

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