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ZD 9379 - ≥98%(HPLC), high purity , CAS No.170142-20-8

Item Number

Z287711

Grouped product items
SKU	Size	Availability	Price	Qty
Z287711-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$183.90

Brain penetrant NMDA antagonist; acts at glycine site

Basic Description

Synonyms	7-Chloro-2,3-dihydro-2-(4-methoxy-2-methylphenyl)pyridazino [4,5-b] quinoline-1,4,10(5H)trione
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	NMDA receptor antagonist; acts at glycine site. Neuroprotective; reduces infarct size and frequency of spreading depressions in a rat model of ischemic stroke. Brain penetrant.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	7-chloro-2-(4-methoxy-2-methylphenyl)-3,5-dihydropyridazino[4,5-b]quinoline-1,4,10-trione
INCHI	InChI=1S/C19H14ClN3O4/c1-9-7-11(27-2)4-6-14(9)23-19(26)15-16(18(25)22-23)21-13-8-10(20)3-5-12(13)17(15)24/h3-8H,1-2H3,(H,21,24)(H,22,25)
InChi Key	PSTDMIAVUUYOOQ-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C=CC(=C1)OC)N2C(=O)C3=C(C(=O)N2)NC4=C(C3=O)C=CC(=C4)Cl
Isomeric SMILES	CC1=C(C=CC(=C1)OC)N2C(=O)C3=C(C(=O)N2)NC4=C(C3=O)C=CC(=C4)Cl
PubChem CID	9843028
Molecular Weight	383.79

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Solubility	Solvent:DMSO, Max Conc. mg/mL: 19.19, Max Conc. mM: 50; Solvent:1eq. NaOH, Max Conc. mg/mL: 7.68, Max Conc. mM: 20

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