Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Zebularine - ≥98% (HPLC), high purity , CAS No.3690-10-6

  • Moligand™
  • ≥98%(HPLC)
Item Number
Z135482
Grouped product items
SKUSizeAvailabilityPrice Qty
Z135482-5mg
5mg
In stock
$9.90
Z135482-25mg
25mg
In stock
$12.90
Z135482-100mg
100mg
In stock
$23.90
Z135482-250mg
250mg
In stock
$44.90
Z135482-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$66.90
Z135482-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$99.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Discover Zebularine by Aladdin Scientific in ≥98% (HPLC) for only $9.90. Available - in Ligands at Aladdin Scientific. DNA methyltransferase (DNMT) inhibitor Tags: Pyrimidines, Six-Membered Heterocyclic Compounds.

View related series
Pyrimidines Six-Membered Heterocyclic Compounds

Basic Description

SynonymsZebularine|3690-10-6|4-Deoxyuridine|Pyrimidin-2-one ribonucleoside|Pyrimidin-2-one beta-ribofuranoside|Pyrimidin-2-one beta-D-ribofuranoside|NSC 309132|CHEBI:46938|1-beta-D-ribofuranosyl-2(1H)-pyrimidinone|1-beta-D-ribofuranosylpyrimidin-2(1H)-one|7A9Y5SX
Specifications & Purity≥98% (HPLC)
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Product Description

Zebularine is a cell-permeable chemically stable cytidine analog and DNA methylation inhibitor which acts by forming a covalent complex with DNMT. It displays antiangiogenic activity and markedly inhibits vessel formation in different tumor models. It reactivates silenced E-cadherin and potentiates the effects of other epigenetic therapeutics such as vorinistat. Induces differentiation of mesenchymal cells into cardiomyocytes. Inhibits cytidine deaminase (CDD).
An inhibitor of DNA methyltransferase

Names and Identifiers

IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
INCHI InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
InChi Key RPQZTTQVRYEKCR-WCTZXXKLSA-N
Canonical SMILES C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
Isomeric SMILES C1=CN(C(=O)N=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
PubChem CID 100016
Molecular Weight 228.20

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

15 results found

Lot NumberCertificate TypeDateItem
K2322168Certificate of AnalysisNov 10, 2023 Z135482
K2322184Certificate of AnalysisNov 10, 2023 Z135482
K2322185Certificate of AnalysisNov 10, 2023 Z135482
K2322186Certificate of AnalysisNov 10, 2023 Z135482
K2322187Certificate of AnalysisNov 10, 2023 Z135482
K2322188Certificate of AnalysisNov 10, 2023 Z135482
K2322189Certificate of AnalysisNov 10, 2023 Z135482
K2322193Certificate of AnalysisNov 10, 2023 Z135482
K2322194Certificate of AnalysisNov 10, 2023 Z135482
K2322197Certificate of AnalysisNov 10, 2023 Z135482
E2117330Certificate of AnalysisMar 09, 2023 Z135482
E2117331Certificate of AnalysisMar 09, 2023 Z135482
E2117332Certificate of AnalysisMar 09, 2023 Z135482
H2331055Certificate of AnalysisMar 09, 2023 Z135482
H1622057Certificate of AnalysisMay 09, 2022 Z135482

more

Chemical and Physical Properties

SolubilitySoluble in DMSO (>25 mg/ml), methanol (5 mg/ml), water (>25 mg/ml), DMF (~5 mg/ml), and ethanol (~0.25 mg/ml).
Sensitivityheat sensitive
Refractive Index1.7
Specific Rotation[α]+156.0 ～ +160.0°(C=1, MeOH)
Boil Point(°C)499.02° C
Melt Point(°C)157-160° C

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Zebularine (NSC 309132) - 10mM in DMSO, used for , CAS No. 3690-10-6(DMSO), by Aladdin Scientific
    Zebularine (NSC 309132)

    Starting at $47.90

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.