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Zerumbone - 10mM in DMSO, high purity , CAS No.471-05-6
Potent NF-κB inhibitor. Anticancer agent.
Basic Description Synonyms Zerumbone | 471-05-6 | (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one | (E,E,E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one | CHEMBL245412 | 2E,6E,9E-humulatrien-8-one | CHEBI:63892 | erumbone | 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one | SCHEM Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Potent NF-κB inhibitor. Anticancer agent. Induces cytochrome c dependent caspase activation and mitochondrial permeabilisation in cancer cells. Induces apoptosis and shows anti-inflammatory and antitumor effects in vivo. Orally active. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one INCHI InChI=1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+ InChi Key GIHNTRQPEMKFKO-SKTNYSRSSA-N Canonical SMILES CC1=CCC(C=CC(=O)C(=CCC1)C)(C)C Isomeric SMILES C/C/1=C\CC(/C=C/C(=O)/C(=C/CC1)/C)(C)C PubChem CID 5470187 Molecular Weight 218.33
Safety and Hazards(GHS) Pictogram(s) GHS09 , GHS07 Signal Warning Hazard Statements H317: May cause an allergic skin reaction
H400: Very toxic to aquatic life
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P391: Collect spillage.
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