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Zimelidine dihydrochloride , Serotonin (5-HT) receptor antagonist, CAS No.61129-30-4, Serotonin (5-HT) receptor antagonist

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Zimelidine dihydrochloride , Serotonin (5-HT) receptor antagonist, CAS No.61129-30-4, Serotonin (5-HT) receptor antagonist

CAS#: 61129-30-4
Formula: C₁₆H₂₁BrCl₂N₂O
Molecular Weight: 408.2
PubChem CID: 6420041

Item Number

Z337892

Grouped product items
SKU	Size	Availability	Price	Qty
Z337892-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$46.90
Z337892-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$275.90

a selective 5-HT uptake inhibitor

Basic Description

Synonyms	CarbidopaMonohydrate \| H 102/09 hydrochloride \| NSC-756672 \| UNII-2T97D1P85R \| ZIMELDINE HYDROCHLORIDE [JAN] \| NCGC00025286-04 \| Zelmid \| Zimeldine HCl \| UNII-U79T955O9J \| HMS1568C06 \| Zimeldine hydrochloride monohydrate \| ZIMELDINE DIHYDROCHLORIDE HYDRAT
Storage Temp	Room temperature,Desiccated
Shipped In	Normal
Action Type	ANTAGONIST
Mechanism of action	Serotonin (5-HT) receptor antagonist
Product Description	Zimelidine dihydrochloride is a selective 5-HT uptake inhibitor; selective over noradrenalin and dopamine uptake (IC\|50\|values are 0.33, 8.2 and 12 μM respectively).

Associated Targets(Human)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(Z)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-3-ylprop-2-en-1-amine;hydrate;dihydrochloride
INCHI	InChI=1S/C16H17BrN2.2ClH.H2O/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13;;;/h3-10,12H,11H2,1-2H3;2*1H;1H2/b16-9-;;;
InChi Key	WFUAVXYXJOQWAZ-GVKRCPFFSA-N
Canonical SMILES	CN(C)CC=C(C1=CC=C(C=C1)Br)C2=CN=CC=C2.O.Cl.Cl
Isomeric SMILES	CN(C)C/C=C(/C1=CC=C(C=C1)Br)\C2=CN=CC=C2.O.Cl.Cl
WGK Germany	3
RTECS	UC6555000
PubChem CID	6420041
Molecular Weight	408.2

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble in water (100 mM), and 0.1M HCl (45 mg/ml).
Refractive Index	n20D1.60 (Predicted)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	UC6555000
Merck Index	14: 10126
RIDADR	NONHforallmodesoftransport

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