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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Z125730-50mg | 50mg | In stock | $195.90 | |
Z125730-100mg | 100mg | In stock | $352.90 | |
Z125730-250mg | 250mg | In stock | $793.90 | |
Z125730-1g | 1g | In stock | $2,857.90 |
Synonyms | CP-88059-27 | AM90310 | ziprasidonum | Ziprasidone [INN:BAN] | D08687 | AB00639925_05 | DTXCID403753 | NCGC00263539-01 | 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indole-2-one | AC-23360 | CHEBI:10119 | ziprazidone | 5 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its m |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST, ANTAGONIST, INHIBITOR |
Mechanism of action | Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 7 receptor;Antagonist of D 2 receptor;Antagonist of H 1 recept |
Product Description | Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one |
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INCHI | InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) |
InChi Key | MVWVFYHBGMAFLY-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54 |
Isomeric SMILES | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54 |
RTECS | NM3241000 |
PubChem CID | 60854 |
Molecular Weight | 412.94 |
Reaxy-Rn | 6669199 |
PubChem CID | 60854 |
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DrugBank Ligand | DB00246 |
CAS Registry No. | 146939-27-7 |
ChEBI | CHEBI:10119 |
Wikipedia | Ziprasidone |
ChEMBL Ligand | CHEMBL708 |
BindingDB Ligand | 50048803 |
PEP | ziprasidone |
DrugCentral Ligand | 2865 |
GPCRdb Ligand | ziprasidone |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
H2212560 | Certificate of Analysis | May 07, 2024 | Z125730 |
H2212563 | Certificate of Analysis | May 07, 2024 | Z125730 |
H2212564 | Certificate of Analysis | May 07, 2024 | Z125730 |
H2212565 | Certificate of Analysis | May 07, 2024 | Z125730 |
Solubility | DMSO |
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Melt Point(°C) | 222 °C |
RTECS | NM3241000 |
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Reaxy-Rn | 6669199 |
Merck Index | 10171 |