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ZM323881 , CAS No.193001-14-8
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Basic Description Synonyms 4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol | 5-((7-(benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol | ZM323881 | ZM-323881 | CS-0986 | 4-fluoro-2-methyl-5-[[7-(phenylmethoxy)-4-quinazolinyl]amino]phenol | NCGC00161416-01 | Biochemical and Physiological Mechanisms ZM323881 is a potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. ZM323881 selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases su
Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol INCHI InChI=1S/C22H18FN3O2/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15/h2-11,13,27H,12H2,1H3,(H,24,25,26) InChi Key NVBNDZZLJRYRPD-UHFFFAOYSA-N Canonical SMILES CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F Isomeric SMILES CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F PubChem CID 16759369 Molecular Weight 375.4
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