Zofenopril-d5 , CAS No.81872-10-8 unlabeled, Inhibitor of Angiotensin-converting enzyme

Item Number

Z333827

• Synonyms: Zofenopril|81872-10-8|Zofenoprilum|Zofenil|CHEMBL331378|DTXSID0046640|CHEBI:78539|290ZY759PI|Zofenopril (INN)|(2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid|NCGC00167455-01|ZOFENOPRIL [INN]|Zofenoprilum
• Specifications & Purity: Moligand™
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of Angiotensin-converting enzyme

Product Description

Zofenopril-d5 Calcium Salt is a compound that is de-esterified into the active inhibitor, Zefenoprilat. Zenoprilat is the active free sulfhydryl compound of Zenopril. Zenopril is an antioxidant that acts as an angiotensin-converting enzyme (ACE) inhibitor. Endothelial membrane studies have demonstrated that Zenoprilat induces the bradykinin B1 receptors, which activates the expression of FGF-2. Studies show that Zofenoprilat is more effective than enalaprilat at protecting pancreatic islets from extended high glucose exposure.