Grouped product items

SKU

Size

Availability

Price

Qty

Z129649-200mg

200mg

In stock

$76.90

Z129649-250mg

250mg

Available within 4-8 weeks(?)

$86.90

Z129649-1g

In stock

$269.90

Z129649-5g

In stock

$1,214.90

Z129649-25g

25g

In stock

$5,463.90

Basic Description

Synonyms	zolmitriptan\|139264-17-8\|Zomig\|Zomigoro\|311C90\|Zomig-ZMT\|Zomigon\|Flezol\|Zomig Nasal Spray\|Zomig ZMT\|zipton\|zolmitriptanum\|zominat\|Rapimelt\|(S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one\|C16H21N3O2\|UNII-2FS66TH3YW\|Cvt-427\|2FS66TH3
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent 5-HT1B/1D/1Fagonist (Kivalues are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1Band h5-HT1Freceptors respectively). Inhibits trigeminal nerve stimulation-mediated neurogenic plasma protein extravasation in guinea pigs; blocks long excitatory postsyna
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Serotonin 1d (5-HT1d) receptor agonist
Product Description	Zolmitriptan is a selective serotonin receptor agonist. A serotonin 5HTID-receptor agonist.

Product Properties

ALogP	2.2

Associated Targets

CNFN Tdark Cornifelin 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNR1 Tclin Cannabinoid receptor 1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

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ESR1 Tclin Estrogen receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCB1 Tchem Multidrug resistance protein 1 0 Activities

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HDAC6 Tclin Histone deacetylase 6 0 Activities

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FAAH Tchem Fatty-acid amide hydrolase 1 0 Activities

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HRH1 Tclin Histamine H1 receptor 0 Activities

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

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PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

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ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

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ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1E Tchem 5-hydroxytryptamine receptor 1E 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1D Tclin 5-hydroxytryptamine receptor 1D 6 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

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HTR1A Tclin 5-hydroxytryptamine receptor 1A 3 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
INCHI	InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
InChi Key	ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Canonical SMILES	CN(C)CCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
Isomeric SMILES	CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
WGK Germany	3
RTECS	RQ2707000
PubChem CID	60857
Molecular Weight	287.36

Database links

PubChem CID	60857
ChEBI	CHEBI:10124
CAS Registry No.	139264-17-8
Wikipedia	Zolmitriptan
ChEMBL Ligand	CHEMBL1185
BindingDB Ligand	50033383
DrugBank Ligand	DB00315
PEP	zolmitriptan
DrugCentral Ligand	2869
GPCRdb Ligand	zolmitriptan

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
G2207411	Certificate of Analysis	Apr 07, 2024	Z129649
G2207412	Certificate of Analysis	Apr 07, 2024	Z129649
G2207414	Certificate of Analysis	Apr 07, 2024	Z129649
B2210166	Certificate of Analysis	Nov 16, 2023	Z129649

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 28.74, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 28.74, Max Conc. mM: 100
Sensitivity	Heat sensitive
Specific Rotation[α]	-4° (C=1,MeOH)
Melt Point(°C)	135-137°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H371:May cause damage to organs
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	RQ2707000
Merck Index	10189

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Zolmitriptan - ≥98%(HPLC), high purity , Serotonin 1d (5-HT1d) receptor agonist, CAS No.139264-17-8, Serotonin 1d (5-HT1d) receptor agonist

Basic Description

Product Properties

Associated Targets

CNFN Tdark Cornifelin 0 Activities

CNR1 Tclin Cannabinoid receptor 1 0 Activities

DRD2 Tclin D(2) dopamine receptor 0 Activities

ESR1 Tclin Estrogen receptor 0 Activities

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

NR3C1 Tclin Glucocorticoid receptor 0 Activities

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

ABCB1 Tchem Multidrug resistance protein 1 0 Activities

HDAC6 Tclin Histone deacetylase 6 0 Activities

FAAH Tchem Fatty-acid amide hydrolase 1 0 Activities

HRH1 Tclin Histamine H1 receptor 0 Activities

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

DRD3 Tclin D(3) dopamine receptor 0 Activities

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

ADORA2A Tclin Adenosine receptor A2a 0 Activities

HTR1E Tchem 5-hydroxytryptamine receptor 1E 1 Activities

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

AR Tclin Androgen receptor 0 Activities

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

HTR1D Tclin 5-hydroxytryptamine receptor 1D 6 Activities

HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities

ADORA1 Tclin Adenosine receptor A1 0 Activities

HTR1A Tclin 5-hydroxytryptamine receptor 1A 3 Activities

ADORA3 Tchem Adenosine receptor A3 0 Activities

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

EDNRA Tclin Endothelin-1 receptor 0 Activities

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

OPRD1 Tclin Delta-type opioid receptor 0 Activities

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

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