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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Z287970-5mg | 5mg | In stock | $117.90 | |
Z287970-10mg | 10mg | In stock | $189.90 | |
Z287970-25mg | 25mg | In stock | $395.90 | |
Z287970-50mg | 50mg | In stock | $642.90 | |
Z287970-100mg | 100mg | In stock | $1,038.90 |
Selective GPR84 agonist
Specifications & Purity | Moligand™, ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | Selective medium-chain free fatty acid receptor GPR84 agonist (EC50= 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desens |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of GPR84 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-hexylsulfanyl-4-hydroxy-1H-pyrimidin-6-one |
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INCHI | InChI=1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14) |
InChi Key | UYXOAKRMLQKLQX-UHFFFAOYSA-N |
Canonical SMILES | CCCCCCSC1=NC(=CC(=O)N1)O |
Isomeric SMILES | CCCCCCSC1=NC(=CC(=O)N1)O |
PubChem CID | 1912564 |
MeSH Entry Terms | 2-(hexylthio)pyrimidine-4,6-diol;ZA-16 compound |
Molecular Weight | 228.31 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H23031038 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031039 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031047 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031048 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031050 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031074 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031076 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031109 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031113 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
H23031120 | Certificate of Analysis | Jul 17, 2023 | Z287970 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 11.42, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 22.83, Max Conc. mM: 100 |
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RIDADR | NONHforallmodesoftransport |
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