ZQ 16 - ≥98%(HPLC), high purity , CAS No.376616-73-8, Agonist of GPR84

Item Number

Z287970

Grouped product items
SKU	Size	Availability	Price
Z287970-5mg	5mg	In stock	$117.90
Z287970-10mg	10mg	In stock	$189.90
Z287970-25mg	25mg	In stock	$395.90
Z287970-50mg	50mg	In stock	$642.90
Z287970-100mg	100mg	In stock	$1,038.90

Selective GPR84 agonist

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Basic Description

Synonyms	2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone;ZQ-16
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Selective medium-chain free fatty acid receptor GPR84 agonist (EC50= 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desens
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of GPR84

Associated Targets(Human)

GPR84 Tchem G-protein coupled receptor 84 (5 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GPR84 Tchem G-protein coupled receptor 84 (1284 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-hexylsulfanyl-4-hydroxy-1H-pyrimidin-6-one
INCHI	InChI=1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
InChi Key	UYXOAKRMLQKLQX-UHFFFAOYSA-N
Canonical SMILES	CCCCCCSC1=NC(=CC(=O)N1)O
Isomeric SMILES	CCCCCCSC1=NC(=CC(=O)N1)O
PubChem CID	1912564
MeSH Entry Terms	2-(hexylthio)pyrimidine-4,6-diol;ZA-16 compound
Molecular Weight	228.31

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
H23031038	Certificate of Analysis	Jul 17, 2023	Z287970
H23031039	Certificate of Analysis	Jul 17, 2023	Z287970
H23031047	Certificate of Analysis	Jul 17, 2023	Z287970
H23031048	Certificate of Analysis	Jul 17, 2023	Z287970
H23031050	Certificate of Analysis	Jul 17, 2023	Z287970
H23031074	Certificate of Analysis	Jul 17, 2023	Z287970
H23031076	Certificate of Analysis	Jul 17, 2023	Z287970
H23031109	Certificate of Analysis	Jul 17, 2023	Z287970
H23031113	Certificate of Analysis	Jul 17, 2023	Z287970
H23031120	Certificate of Analysis	Jul 17, 2023	Z287970

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Basic Description