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EED
Description | Polycomb protein EED |
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Gene and Protein Information
Gene ID | 8726 |
Uniprot Accession IDs | A8K7V5 O00149 Q6NTH2 Q7LDA5 Q7LDG8 Q86VV2 Q9UNY7 hEED |
Ensembl ID | ENSP00000263360 |
Symbol | HEED COGIS WAIT1 |
Family | Belongs to the WD repeat ESC family. |
Sequence | MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Macaque | 703866 | EED | embryonic ectoderm development | 9544 | | Inparanoid, OMA, EggNOG |
Mouse | 13626 | Eed | embryonic ectoderm development | 10090 | MGI:95286 | Inparanoid, OMA, EggNOG |
Rat | 293104 | Eed | embryonic ectoderm development | 10116 | RGD:1309782 | Inparanoid, OMA, EggNOG |
Dog | 476779 | EED | embryonic ectoderm development | 9615 | VGNC:40206 | Inparanoid, OMA, EggNOG |
Horse | 100061139 | EED | embryonic ectoderm development | 9796 | VGNC:17428 | Inparanoid, OMA, EggNOG |
Cow | 404183 | EED | embryonic ectoderm development | 9913 | VGNC:28332 | Inparanoid, OMA, EggNOG |
Pig | 100521029 | EED | embryonic ectoderm development | 9823 | | OMA, EggNOG |
Opossum | 100026010 | EED | embryonic ectoderm development | 13616 | | Inparanoid, OMA, EggNOG |
Platypus | 100080634 | EED | embryonic ectoderm development | 9258 | | Inparanoid, OMA, EggNOG |
Chicken | 426381 | MIR6755 | microRNA 6755 | 9031 | CGNC:10494 | Inparanoid, OMA |
Anole lizard | 100566610 | eed | embryonic ectoderm development | 28377 | | Inparanoid, OMA, EggNOG |
Xenopus | 550079 | eed | embryonic ectoderm development | 8364 | XB-GENE-491480 | Inparanoid, OMA, EggNOG |
Zebrafish | 550463 | eed | embryonic ectoderm development | 7955 | ZDB-GENE-050417-287 | Inparanoid, OMA |
C. elegans | 177657 | mes-6 | Polycomb protein mes-6 | 6239 | | Inparanoid, OMA, EggNOG |
Fruitfly | 34595 | esc | extra sexcombs | 7227 | FBgn0000588 | Inparanoid, EggNOG |
Associated Recombinant Proteins
Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
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Associated Active Ligands
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A-395 8-(6-Cyclopropylpyridin-3-yl)-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine 8-(6-(Difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine 12-(((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-4-isopropyl-7-(trifluoromethyl)-4,5-dihydro-3H-2,4,8,11,12a-pentaozabenzo[4,5]cycloocta[1,2,3-cd]inden-3-one rac-1-(4-(4-((3S,4R)-4-(dimethylamino)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl)phenyl)piperazin-1-yl)ethanone 1-(4-(4-((3S,4R)-4-(dimethylamino)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl)phenyl)piperazin-1-yl)ethanone rac-(1S,2R)-4-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-2-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)cyclopentanamine 1-(4-(4-((3S,4R)-4-(Dimethylamino)-1-((S)-7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl)phenyl)piperazin-1-yl)ethanone (3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-1-(methylsulfonyl)-8-(6-(trifluoromethyl)pyridin-3-yl)imidazo[1,5-c]pyrimidin-5-amine
Associated Diseases
Name | Direct Associated Targets | Disease Type | Mondoid |
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